Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR2 | P25090 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | XBP1 | P17861 | 1/20 | 0.46 |
| ▸ | AAK1 | Q2M2I8 | 5/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.43 |
| ▸ | MEN1 | O00255 | 5/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | NPR3 | P17342 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19563339 | 1.00 | FPR2 (0.46) | FPR2MAPTLMNAMAPK1GAA | |
| SCHEMBL19563283 | 0.85 | UTS2R (0.44) | FPR2MAPTLMNAKMT2AMEN1 | |
| SCHEMBL16748770 | 0.85 | UTS2R (0.44) | FPR2MAPTLMNAKMT2AMEN1 | |
| SCHEMBL16748863 | 0.85 | FPR2 (0.47) | FPR2MAPTLMNAMAPK1GAA | |
| SCHEMBL19563290 | 0.85 | FPR2 (0.47) | FPR2MAPTLMNAMAPK1GAA | |
| SCHEMBL16748862 | 0.84 | FPR2 (0.48) | FPR2MAPTLMNAMAPK1GAA | |
| SCHEMBL18086998 | 0.83 | FPR2 (0.50) | FPR2MAPTKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL16742520 | 0.83 | FPR2 (0.57) | FPR2KMT2AMEN1SMN1; SMN2CYP1A2 | |
| SCHEMBL16742517 | 0.83 | FPR2 (0.57) | FPR2KMT2AMEN1SMN1; SMN2CYP1A2 | |
| SCHEMBL19563366 | 0.82 | AAK1 (0.41) | FPR2MAPTLMNAMAPK1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3071548-B1 | PHENYLCARBAMATE DERIVATIVES AS FORMYL PEPTIDE RECEPTOR MODULATORS | ALLERGAN INC (US) | 2017-11-08 | — | — | EP | claimed |
| US-9926264-B2 | Phenylcarbamate derivatives as formyl peptide receptor modulators | ALLERGAN, INC. (US) | 2018-03-27 | — | — | US | disclosed |
| US-9926264-B2 | Phenylcarbamate derivatives as formyl peptide receptor modulators | ALLERGAN, INC. (US) | 2018-03-27 | — | — | US | disclosed |
| EP-3071548-B1 | PHENYLCARBAMATE DERIVATIVES AS FORMYL PEPTIDE RECEPTOR MODULATORS | ALLERGAN INC (US) | 2017-11-08 | — | — | EP | disclosed |
| US-20160272581-A1 | PHENYLCARBAMATE DERIVATIVES AS FORMYL PEPTIDE RECEPTOR MODULATORS | ALLERGAN, INC. (US) | 2016-09-22 | — | — | US | disclosed |
| US-20160272581-A1 | PHENYLCARBAMATE DERIVATIVES AS FORMYL PEPTIDE RECEPTOR MODULATORS | ALLERGAN, INC. (US) | 2016-09-22 | — | — | US | disclosed |
| WO-2015077451-A1 | PHENYLCARBAMATE DERIVATIVES AS FORMYL PEPTIDE RECEPTOR MODULATORS | ALLERGAN, INC. (US) | 2015-05-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160272581-A1 | PHENYLCARBAMATE DERIVATIVES AS FORMYL PEPTIDE RECEPTOR MODULATORS | FPR2, FPR1, FPR3 | FPR2 1/4885MAPT 3521/4885LMNA 4255/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.