SCHEMBL19565366

SCHEMBL19565366

CCCCCCCCCCCCCCCCCCOc1cc(C(=O)n2c(=O)c(C)cn([C@H]3CC(O[Si](C)(C)C(C)(C)C)[C@@H](CC)O3)c2=O)cc(OCCCCCCCCCCCCCCCCCC)c1OCCCCCCCCCCCCCCCCCC

nearest known ligand 0.39

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
TOP2A P11388 4/20 0.32
TK2 O00142 1/20 0.30
THRA P10827 1/20 0.30
THRB P10828 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19565375 0.83 TOP2A (0.35) TOP2ATK2
SCHEMBL29703141 0.82 TK2 (0.39) TK2
SCHEMBL26233448 0.82 RNASE1 (0.42) TOP2ATK2
SCHEMBL17230899 0.80 RNASE1 (0.38) TK2THRATHRB
SCHEMBL889667 0.78 TOP2A (0.34) TOP2A
SCHEMBL29703140 0.77 PLA2G2A (0.30)
SCHEMBL21563857 0.76 TOP2A (0.42) TOP2ATK2
SCHEMBL17230947 0.74 RNASE1 (0.38) TK2
SCHEMBL17230895 0.74 TYMP (0.40)
SCHEMBL4731815 0.73 RNASE1 (0.44) TOP2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170320904-A1 PRECIPITATION PROMOTER AND PRECIPITATION METHOD IN WHICH SAME IS USED AJINOMOTO CO., INC. (JP) 2017-11-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170320904-A1 PRECIPITATION PROMOTER AND PRECIPITATION METHOD IN WHICH SAME IS USED SP1, MED25, CTCF TOP2A 1010/4885TK2 1838/4885THRA 4084/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.