Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 13/20 | 0.56 |
| ▸ | CTSL | P07711 | 7/20 | 0.54 |
| ▸ | CTSB | P07858 | 7/20 | 0.54 |
| ▸ | CTSH | P09668 | 5/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2179628 | 0.90 | CTSK (0.45) | CTSKCTSLCTSBCTSH | |
| SCHEMBL1227603 | 0.80 | CTSK (0.60) | CTSKCTSLCTSBCTSH | |
| SCHEMBL10894386 | 0.79 | CTSK (0.38) | CTSKCTSLCTSBCTSH | |
| SCHEMBL25021345 | 0.78 | CTSK (0.57) | CTSKCTSLCTSBCTSH | |
| SCHEMBL16746653 | 0.75 | CTSK (0.50) | CTSKCTSLCTSBCTSH | |
| SCHEMBL13243836 | 0.75 | CTSL (0.72) | CTSKCTSLCTSBCTSH | |
| SCHEMBL7796292 | 0.75 | CTSK (0.41) | CTSKCTSLCTSBCTSH | |
| SCHEMBL11090131 | 0.75 | CTSK (0.41) | CTSKCTSLCTSBCTSH | |
| SCHEMBL25022548 | 0.74 | CTSK (0.54) | CTSKCTSLCTSBCTSH | |
| SCHEMBL11231610 | 0.73 | CTSK (0.47) | CTSKCTSLCTSBCTSH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017193034-A1 | MODULATORS OF THE INTEGRATED STRESS PATHWAY | CALICO LIFE SCIENCES (US) | 2017-11-09 | — | — | WO | disclosed |