Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 7/20 | 0.72 |
| ▸ | CTSB | P07858 | 7/20 | 0.72 |
| ▸ | CTSH | P09668 | 5/20 | 0.72 |
| ▸ | CTSK | P43235 | 17/20 | 0.67 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19569610 | 0.75 | CTSK (0.56) | CTSLCTSBCTSHCTSK | |
| SCHEMBL1227603 | 0.73 | CTSK (0.60) | CTSLCTSBCTSHCTSK | |
| SCHEMBL25021345 | 0.71 | CTSK (0.57) | CTSLCTSBCTSHCTSK | |
| SCHEMBL16746653 | 0.69 | CTSK (0.50) | CTSLCTSBCTSHCTSK | |
| SCHEMBL25022548 | 0.68 | CTSK (0.54) | CTSLCTSBCTSHCTSK | |
| SCHEMBL28296546 | 0.67 | CTSK (0.46) | CTSLCTSBCTSHCTSK | |
| SCHEMBL192070 | 0.67 | CTSK (0.47) | CTSLCTSBCTSHCTSK | |
| SCHEMBL11231610 | 0.67 | CTSK (0.47) | CTSLCTSBCTSHCTSK | |
| SCHEMBL24308309 | 0.66 | CTSK (0.47) | CTSLCTSBCTSHCTSK | |
| SCHEMBL2616310 | 0.66 | CTSK (0.46) | CTSLCTSBCTSHCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8771644-B2 | Imaging probes | SANOFI (FR) | 2014-07-08 | — | — | US | disclosed |
| US-20100189658-A1 | Imaging probes | SANOFI-AVENTIS (FR) | 2010-07-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100189658-A1 | Imaging probes | CTSV, CTSL, CTSB | CTSL 2/4885CTSB 3/4885CTSH 16/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.