SCHEMBL19569732

SCHEMBL19569732

O=c1ccc2c(-c3c(S(=O)(=O)O)cc(Br)cc3S(=O)(=O)O)c3ccc(O)cc3oc-2c1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
USP2 O75604 3/20 0.59
MEN1 O00255 3/20 0.59
KMT2A Q03164 3/20 0.59
POLB P06746 2/20 0.59
ATM Q13315 1/20 0.59
PLEC Q15149 1/20 0.59
L3MBTL1 Q9Y468 1/20 0.52
ALPL P05186 1/20 0.50
ALPI P09923 1/20 0.50
ALPG P10696 1/20 0.50
CA9 Q16790 12/20 0.45
CA1 P00915 10/20 0.45
CA2 P00918 10/20 0.45
CA12 O43570 3/20 0.43
DNASE1L3 Q13609 1/20 0.43
PRMT1 Q99873 1/20 0.43
CDC25A P30304 1/20 0.43
CDC25B P30305 1/20 0.43
CDC25C P30307 1/20 0.43
CA14 Q9ULX7 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19564789 0.90 USP2 (0.58) USP2MEN1KMT2APOLBATM
SCHEMBL13045870 0.83 USP2 (0.67) USP2MEN1KMT2APOLBATM
SCHEMBL19564791 0.80 USP2 (0.49) USP2MEN1KMT2APOLBATM
SCHEMBL26351340 0.79 USP2 (0.60) USP2MEN1KMT2APOLBATM
SCHEMBL3654824 0.79 USP2 (0.58) USP2MEN1KMT2APOLBATM
SCHEMBL13211048 0.78 USP2 (0.55) USP2MEN1KMT2APOLBATM
SCHEMBL25024679 0.78 USP2 (0.54) USP2MEN1KMT2APOLBATM
SCHEMBL12677052 0.78 USP2 (0.54) USP2MEN1KMT2APOLBATM
SCHEMBL19615424 0.75 USP2 (0.62) USP2MEN1KMT2APOLBATM
SCHEMBL940682 0.74 MEN1 (1.00) USP2MEN1KMT2APOLBATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10370351-B2 Photoinduced electron transfer voltage-sensitive compounds THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2019-08-06 US disclosed
US-20170320846-A1 PHOTOINDUCED ELECTRON TRANSFER VOLTAGE-SENSITIVE COMPOUNDS NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2017-11-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10370351-B2 Photoinduced electron transfer voltage-sensitive compounds VDAC1, VDAC3, VDAC2 USP2 3927/4885MEN1 3178/4885KMT2A 3225/4885
US-20170320846-A1 PHOTOINDUCED ELECTRON TRANSFER VOLTAGE-SENSITIVE COMPOUNDS VDAC1, VDAC3, VDAC2 USP2 3927/4885MEN1 3178/4885KMT2A 3225/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.