SCHEMBL19569860

SCHEMBL19569860

CC(C)Oc1ccc(N=O)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A3 P47895 1/20 0.52
KMT2A Q03164 3/20 0.50
PARP10 Q53GL7 1/20 0.48
POLB P06746 1/20 0.46
GLA P06280 1/20 0.44
ALDH1A1 P00352 5/20 0.42
SCN5A Q14524 1/20 0.42
SCN2A Q99250 1/20 0.42
TP53 P04637 3/20 0.41
MAPK1 P28482 2/20 0.41
TSHR P16473 1/20 0.41
HIF1A Q16665 1/20 0.41
HSD17B10 Q99714 1/20 0.41
LMNA P02545 4/20 0.41
GAA P10253 2/20 0.41
NPC1 O15118 1/20 0.41
RAB9A P51151 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
BRD4 O60885 1/20 0.39
BRPF1 P55201 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL125543 0.80 ALDH1A3 (0.64) ALDH1A3KMT2APARP10POLBGLA
SCHEMBL9111062 0.78 ALDH1A3 (0.53) ALDH1A3KMT2APARP10POLBGLA
SCHEMBL15780502 0.77 ACACB (0.38) ALDH1A1TP53MAPK1TSHRHIF1A
SCHEMBL5501717 0.76 P2RY6 (0.48) ALDH1A3KMT2APARP10POLBGLA
SCHEMBL14607276 0.75 KMT2A (0.49) KMT2APOLBALDH1A1TSHRHSD17B10
Hydrogen Peroxide SCHEMBL28902806 0.75 KMT2A (0.70) ALDH1A3KMT2APARP10POLBGLA
SCHEMBL18836850 0.74 PARP10 (0.46) ALDH1A3KMT2APARP10POLBGLA
SCHEMBL1805832 0.73 ALDH1A3 (0.58) ALDH1A3KMT2APARP10POLBGLA
SCHEMBL156005 0.73 CA1 (0.58) KMT2AALDH1A1TP53MAPK1TSHR
SCHEMBL6138149 0.72 HTR3E (0.62) PARP10POLBGLASCN5ASCN2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240066133-A1 THERAPEUTIC AGENTS AND CONJUGATES THEREOF AJ SCIENCES (YIXING) CO., LTD (CN) 2024-02-29 US disclosed
US-11572398-B2 GLP-1 derivatives and uses thereof NOVO NORDISK A/S (DK) 2023-02-07 US disclosed
US-20210332082-A1 TRACELESS REDUCTIVELY CLEAVABLE LINKER MOLECULES FOR PEPTIDE PURIFICATION Belyntic GmbH (DE) 2021-10-28 US disclosed
US-20210206799-A1 LINKER MOLECULE AND USE THEREOF IN METHODS FOR PURIFYING PEPTIDES Belyntic GmbH (DE) 2021-07-08 US disclosed
US-10954266-B2 Linker molecule and use thereof in methods for purifying peptides Belyntic GmbH (DE) 2021-03-23 US disclosed
US-20190309013-A1 LINKER MOLECULE AND USE THEREOF IN METHODS FOR PURIFYING PEPTIDES Belyntic GmbH (DE) 2019-10-10 US disclosed
US-20170320927-A1 GLP-1 Derivatives and Uses Thereof NOVO NORDISK A/S (DK) 2017-11-09 US disclosed
US-20170253607-A1 LONG-ACTING HIV PROTEASE INHIBITOR SHIONOGI & CO., LTD. (JP) 2017-09-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190309013-A1 LINKER MOLECULE AND USE THEREOF IN METHODS FOR PURIFYING PEPTIDES SPPL2B, VIP, SPPL2A ALDH1A3 3716/4885KMT2A 3459/4885PARP10 764/4885
US-20210332082-A1 TRACELESS REDUCTIVELY CLEAVABLE LINKER MOLECULES FOR PEPTIDE PURIFICATION VIP, NGLY1, HM13 ALDH1A3 3512/4885KMT2A 2344/4885PARP10 3367/4885
US-20210206799-A1 LINKER MOLECULE AND USE THEREOF IN METHODS FOR PURIFYING PEPTIDES SPPL2B, SPPL2A, VIP ALDH1A3 4008/4885KMT2A 2761/4885PARP10 771/4885
US-20170253607-A1 LONG-ACTING HIV PROTEASE INHIBITOR CPN1, HAT1, PRSS1 ALDH1A3 3419/4885KMT2A 1478/4885PARP10 2057/4885
US-11572398-B2 GLP-1 derivatives and uses thereof GLP1R, GIPR, GCG ALDH1A3 4153/4885KMT2A 4053/4885PARP10 3168/4885
US-20170320927-A1 GLP-1 Derivatives and Uses Thereof GLP1R, GIPR, GCG ALDH1A3 4153/4885KMT2A 4053/4885PARP10 3168/4885
US-20240066133-A1 THERAPEUTIC AGENTS AND CONJUGATES THEREOF TLR9, STING1, TLR3 ALDH1A3 4735/4885KMT2A 812/4885PARP10 685/4885
US-10954266-B2 Linker molecule and use thereof in methods for purifying peptides SPPL2B, VIP, SPPL2A ALDH1A3 3716/4885KMT2A 3459/4885PARP10 764/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.