SCHEMBL195704

SCHEMBL195704

O=C1OC(=O)c2c1cc(Br)c(Br)c2Br

nearest known ligand 0.52

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.52
ALOX15 P16050 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
AHR P35869 1/20 0.33
TYMS P04818 1/20 0.31
ALOX5 P09917 1/20 0.31
ALDH1A1 P00352 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30443943 1.00 TSHR (0.52) TSHRALOX15TDP1AHRTYMS
SCHEMBL127148 0.78 TSHR (0.46) TSHRALOX15TDP1AHRTYMS
SCHEMBL855808 0.76 ALOX15 (0.48) TSHRALOX15TDP1AHRTYMS
SCHEMBL29768809 0.76 TSHR (0.42) TSHRALOX15TDP1TYMSALDH1A1
SCHEMBL127904 0.76 TSHR (0.42) TSHRALOX15TDP1TYMSALDH1A1
SCHEMBL855919 0.74 TSHR (0.46) TSHRALOX15TDP1TYMSALDH1A1
SCHEMBL127961 0.74 TSHR (0.41) TSHRALOX15TDP1TYMSALDH1A1
SCHEMBL29462451 0.74 TSHR (0.46) TSHRALOX15TDP1TYMSALDH1A1
SCHEMBL854142 0.74 CA1 (0.46) TSHRALOX15TDP1AHRTYMS
SCHEMBL29501815 0.74 ALOX15 (0.43) TSHRALOX15TDP1TYMSALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 61 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111286083-A Bromine flame retardant and preparation method thereof 广州埃登达化工有限公司 2020-06-16 CN claimed
US-5208366-A Catalytic esterification of of aromatic acids or anhydrides containing halogen ELF ATOCHEM NORTH AMERICA, INC. (US) 1993-05-04 US claimed
EP-0334951-A4 HIGH YIELD METHOD FOR PREPARATION OF DIALKYL ESTERS OF POLYHALOAROMATIC ACIDS 1991-03-13 EP claimed
EP-0334951-A1 HIGH YIELD METHOD FOR PREPARATION OF DIALKYL ESTERS OF POLYHALOAROMATIC ACIDS PENNWALT CORPORATION (US) 1989-10-04 EP claimed
WO-1989002887-A2 HIGH YIELD METHOD FOR PREPARATION OF DIALKYL ESTERS OF POLYHALOAROMATIC ACIDS PENNWALT CORPORATION (US) 1989-04-06 WO claimed
CN-118599234-A Styrene resin composition, flame-retardant styrene resin composition, molded article, and patch antenna PS日本株式会社 2024-09-06 CN disclosed
CN-115087702-B Styrene resin composition, flame-retardant styrene resin composition, molded article, and patch antenna PS日本株式会社 2024-05-31 CN disclosed
CN-117342998-A Diamine monomer containing N-aminophthalimide structure, preparation method thereof, polyimide compound and application 浙江工业大学 2024-01-05 CN disclosed
US-20230323137-A1 COMPOSITION FOR SEALING COATED ELECTRIC WIRE, AND COATED ELECTRIC WIRE TOAGOSEI CO. LTD. (JP) 2023-10-12 US disclosed
CN-115087702-A Styrene resin composition, flame-retardant styrene resin composition, molded article, and patch antenna PS日本株式会社 2022-09-20 CN disclosed
EP-3260509-B1 2-CYANOACRYLATE ADHESIVE COMPOSITION TOAGOSEI CO LTD (JP) 2021-04-07 EP disclosed
WO-2021060390-A1 COMPOSITION FOR COVERED-WIRE SEAL AND COVERED WIRE 東亞合成株式会社 2021-04-01 WO disclosed
WO-1991016389-A1 FIRE RESISTANT HYDRAULIC FLUIDS ATOCHEM NORTH AMERICA, INC. (US) 1991-10-31 WO disclosed
US-5049697-A Esterification ATOCHEM NORTH AMERICA, INC. (US) 1991-09-17 US disclosed
EP-0363647-A2 Fire resistant hydraulic fluids ATOCHEM NORTH AMERICA, INC. (a Pennsylvania corp.) (US) 1990-04-18 EP disclosed
EP-0319916-A2 4,4'-Bis(phthalimid)diphenyl sulfone compounds, processes for their production and flame retardant polymer compositions containing them Tosoh Corporation (JP) 1989-06-14 EP disclosed
US-4564697-A HALOGENATED CYCLIC ANHYDRIDE,ALIPHATICPOLYOL, EPOXIDE POTASSIUM CARBOXYLATE ETHYL CORPORATION (US) 1986-01-14 US disclosed
US-4515964-A Polyhalophthalimidoalkyl-functional carbonates PPG INDUSTRIES, INC. (US) 1985-05-07 US disclosed
US-4414396-A FIREPROOFING PPG INDUSTRIES, INC. (US) 1983-11-08 US disclosed
US-4144288-A Sodium tetraborate pentahydrate as a smoke suppressant for styrenic resins PENNWALT CORPORATION (US) 1979-03-13 US disclosed