SCHEMBL127148

SCHEMBL127148

O=C1OC(=O)c2c(Br)c(Br)c3c4c(c(Br)cc1c24)C(=O)OC3=O

nearest known ligand 0.46

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.46
ALOX15 P16050 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
TYMS P04818 1/20 0.32
AHR P35869 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4904796 0.92 TSHR (0.39) TSHRALOX15TDP1TYMS
SCHEMBL29768809 0.92 TSHR (0.42) TSHRALOX15TDP1TYMS
SCHEMBL127904 0.92 TSHR (0.42) TSHRALOX15TDP1TYMS
SCHEMBL127961 0.90 TSHR (0.41) TSHRALOX15TDP1TYMS
SCHEMBL128103 0.85 TYMS (0.41) TSHRALOX15TDP1TYMS
SCHEMBL13713810 0.81 TSHR (0.34) TSHRALOX15TDP1TYMS
SCHEMBL127867 0.79 TSHR (0.54) TSHRALOX15TDP1TYMS
SCHEMBL125842 0.78 TSHR (0.72) TSHRALOX15TDP1
SCHEMBL195704 0.78 TSHR (0.52) TSHRALOX15TDP1TYMSAHR
SCHEMBL30443943 0.78 TSHR (0.52) TSHRALOX15TDP1TYMSAHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150123090-A1 METHOD FOR THE DEPOSITION OF AN ORGANIC MATERIAL BASF SE (DE) 2015-05-07 US disclosed
US-20150123090-A1 METHOD FOR THE DEPOSITION OF AN ORGANIC MATERIAL BASF SE (DE) 2015-05-07 US disclosed
WO-2013164761-A1 METHOD FOR THE DEPOSITION OF AN ORGANIC MATERIAL BASF SE (DE) 2013-11-07 WO disclosed
EP-2532663-A1 Naphthalenecarboxylic acid derivatives and their use as semiconductors BASF SE (DE) 2012-12-12 EP disclosed
US-8309728-B2 Naphthalenetetracarboxylic acid derivatives and their use as semiconductors BASF AKTIENGESELLSCHAFT (DE) 2012-11-13 US disclosed
US-8309728-B2 Naphthalenetetracarboxylic acid derivatives and their use as semiconductors BASF AKTIENGESELLSCHAFT (DE) 2012-11-13 US disclosed
US-20120059168-A1 NAPHTHALENETETRACARBOXYLIC ACID DERIVATIVES AND THEIR USE AS SEMICONDUCTORS BASF SE (DE) 2012-03-08 US disclosed
US-20120059168-A1 NAPHTHALENETETRACARBOXYLIC ACID DERIVATIVES AND THEIR USE AS SEMICONDUCTORS BASF SE (DE) 2012-03-08 US disclosed
US-8084603-B2 Naphthalenetetracarboxylic acid derivatives and their use as semiconductors BASF AKTIENGESELLSCHAFT (DE) 2011-12-27 US disclosed
US-8084603-B2 Naphthalenetetracarboxylic acid derivatives and their use as semiconductors BASF AKTIENGESELLSCHAFT (DE) 2011-12-27 US disclosed
US-20080300405-A1 Naphthalenetetracarboxylic Aicd Derivatives and their Use as Semiconductors BASF SE (DE) 2008-12-04 US disclosed
US-20080300405-A1 Naphthalenetetracarboxylic Aicd Derivatives and their Use as Semiconductors BASF SE (DE) 2008-12-04 US disclosed
WO-2007074137-A1 NAPHTHALENETETRACARBOXYLIC ACID DERIVATIVES AND THEIR USE AS SEMICONDUCTORS BASF SE (DE) 2007-07-05 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120059168-A1 NAPHTHALENETETRACARBOXYLIC ACID DERIVATIVES AND THEIR USE AS SEMICONDUCTORS TST, NANS, NCDN TSHR 3872/4885ALOX15 2912/4885TDP1 4130/4885
US-20080300405-A1 Naphthalenetetracarboxylic Aicd Derivatives and their Use as Semiconductors ADSL, ALAD, EED TSHR 4522/4885ALOX15 2871/4885TDP1 4282/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.