Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | F10 | P00742 | 1/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.39 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.39 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.39 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14853409 | 0.83 | CHRM2 (0.59) | SMN1; SMN2RAB9AMEN1KMT2ACHRM2 | |
| SCHEMBL11981522 | 0.83 | L3MBTL1 (0.45) | L3MBTL1SMN1; SMN2MEN1KMT2ALMNA | |
| SCHEMBL8399380 | 0.82 | MEN1 (0.51) | L3MBTL1SMN1; SMN2RAB9AMEN1KMT2A | |
| SCHEMBL10045143 | 0.82 | L3MBTL1 (0.64) | L3MBTL1MCHR1SMN1; SMN2RAB9ACACNA1G | |
| SCHEMBL10045173 | 0.81 | L3MBTL1 (0.62) | L3MBTL1MCHR1SMN1; SMN2LMNACHRM2 | |
| SCHEMBL10045171 | 0.81 | L3MBTL1 (0.62) | L3MBTL1MCHR1SMN1; SMN2LMNACHRM2 | |
| SCHEMBL12997107 | 0.80 | F10 (0.49) | L3MBTL1SMN1; SMN2RAB9AKMT2ALMNA | |
| SCHEMBL11960431 | 0.79 | HDAC3 (0.56) | KMT2A | |
| SCHEMBL19571325 | 0.79 | MEN1 (0.43) | L3MBTL1SMN1; SMN2RAB9AMEN1KMT2A | |
| SCHEMBL11825 | 0.79 | L3MBTL1 (0.43) | L3MBTL1SMN1; SMN2RAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10259825-B2 | Antimicrobial compounds and methods of making and using the same | MELINTA THERAPEUTICS, INC. (US) | 2019-04-16 | — | — | US | disclosed |
| US-20170320892-A1 | Antimicrobial Compounds And Methods Of Making And Using The Same | SILICON VALLEY BANK | 2017-11-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10259825-B2 | Antimicrobial compounds and methods of making and using the same | LPO, MPO, CAT | L3MBTL1 577/4885MCHR1 3280/4885SMN1; SMN2 3970/4885 |
| US-20170320892-A1 | Antimicrobial Compounds And Methods Of Making And Using The Same | LPO, MPO, CAT | L3MBTL1 577/4885MCHR1 3280/4885SMN1; SMN2 3970/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.