SCHEMBL19575401 — predicted protein targets

Predicted protein targets (top 11)

	gene	UniProt	supporting neighbours	confidence
▸	YTHDC1	Q96MU7	7/20	0.37

▸	MAPK1	P28482	2/20	0.35

▸	ROCK2	O75116	1/20	0.35

▸	KDM4E	B2RXH2	1/20	0.35

▸	ALDH1A1	P00352	1/20	0.35

▸	LMNA	P02545	1/20	0.35

▸	MAPT	P10636	1/20	0.35

▸	HTT	P42858	1/20	0.35

▸	SMN1; SMN2	Q16637	1/20	0.35

▸	BCHE	P06276	1/20	0.34

▸	NR3C2	P08235	2/20	0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL26212056	0.82	ADCY5 (0.46)	ALDH1A1LMNASMN1; SMN2
SCHEMBL19575472	0.82	ADCY5 (0.46)	ALDH1A1LMNASMN1; SMN2
SCHEMBL26224018	0.74	P2RY1 (0.42)	YTHDC1
SCHEMBL20974516	0.71	NSD3 (0.53)	LMNASMN1; SMN2
SCHEMBL26217256	0.71	NR3C1 (0.38)	ALDH1A1
SCHEMBL19575394	0.71	NSD3 (0.53)	LMNASMN1; SMN2
SCHEMBL19575471	0.71	NSD3 (0.53)	LMNASMN1; SMN2
SCHEMBL19575403	0.70	ADCY5 (0.51)	ALDH1A1LMNASMN1; SMN2
SCHEMBL20972815	0.70	ADCY5 (0.51)	ALDH1A1LMNASMN1; SMN2
SCHEMBL19575466	0.70	CDK1 (0.40)	—

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2017191297-A1	ADENINE DERIVATIVES AS PROTEIN KINASE INHIBITORS	BCI PHARMA (FR)	2017-11-09	—	—	WO	disclosed