Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC34A2 | O95436 | 1/20 | 0.42 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.37 |
| ▸ | KDM5A | P29375 | 2/20 | 0.35 |
| ▸ | KDM5B | Q9UGL1 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | KDM5C | P41229 | 1/20 | 0.35 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | SMYD2 | Q9NRG4 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | KDM4A | O75164 | 1/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19579983 | 0.89 | SLC34A2 (0.46) | SLC34A2KDM4ELRRK2MAPTTSHR | |
| SCHEMBL19580023 | 0.89 | SLC34A2 (0.41) | SLC34A2LMNAKMT2AMEN1KDM4C | |
| SCHEMBL19579937 | 0.88 | LMNA (0.43) | SLC34A2TSHRALDH1A1LMNAKMT2A | |
| SCHEMBL19595685 | 0.88 | SLC34A2 (0.46) | SLC34A2LRRK2MAPTSMN1; SMN2KMT2A | |
| SCHEMBL39824 | 0.87 | SLC34A2 (0.44) | SLC34A2KDM5AKDM5BKDM4EKDM5C | |
| SCHEMBL46435 | 0.87 | SLC34A2 (0.47) | SLC34A2KDM5AKDM5BKDM4EKDM5C | |
| SCHEMBL19579995 | 0.86 | SLC34A2 (0.43) | SLC34A2LRRK2MAPTTSHRALDH1A1 | |
| SCHEMBL19580004 | 0.86 | SLC34A2 (0.52) | SLC34A2HDAC1PARP1 | |
| SCHEMBL19579947 | 0.86 | SLC34A2 (0.53) | SLC34A2SMYD2HDAC1 | |
| SCHEMBL19579984 | 0.85 | SLC34A2 (0.46) | SLC34A2ALDH1A1KMT2AMEN1HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2590656-B1 | COMPOUNDS AND METHODS FOR INHIBITING PHOSPHATE TRANSPORT | ARDELYX INC (US) | 2017-11-15 | — | — | EP | claimed |