Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC34A2 | O95436 | 1/20 | 0.54 |
| ▸ | CRHBP | P24387 | 2/20 | 0.39 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.39 |
| ▸ | BRAF | P15056 | 3/20 | 0.38 |
| ▸ | RAF1 | P04049 | 2/20 | 0.38 |
| ▸ | KDR | P35968 | 2/20 | 0.37 |
| ▸ | SRPK2 | P78362 | 1/20 | 0.37 |
| ▸ | SRPK1 | Q96SB4 | 1/20 | 0.37 |
| ▸ | SRPK3 | Q9UPE1 | 1/20 | 0.37 |
| ▸ | TEK | Q02763 | 3/20 | 0.37 |
| ▸ | LCK | P06239 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 2/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL45535 | 0.92 | SLC34A2 (0.64) | SLC34A2BRAFRAF1KDRSRPK2 | |
| SCHEMBL5999719 | 0.91 | SLC34A2 (0.65) | SLC34A2BRAFRAF1LMNATRPV1 | |
| SCHEMBL19580034 | 0.90 | SLC34A2 (0.59) | SLC34A2BRAFRAF1KDRSRPK2 | |
| SCHEMBL19579982 | 0.89 | SLC34A2 (0.53) | SLC34A2BRAFRAF1LMNAKDM1A | |
| SCHEMBL19579969 | 0.89 | SLC34A2 (0.52) | SLC34A2CRHBPCRHR2BRAFRAF1 | |
| SCHEMBL19579933 | 0.89 | SLC34A2 (0.56) | SLC34A2CRHBPCRHR2BRAFRAF1 | |
| SCHEMBL19579976 | 0.89 | SLC34A2 (0.63) | SLC34A2BRAFRAF1KDRSRPK2 | |
| SCHEMBL39856 | 0.88 | SLC34A2 (0.54) | SLC34A2BRAFRAF1KDRSRPK2 | |
| SCHEMBL19579996 | 0.88 | SLC34A2 (0.56) | SLC34A2BRAFRAF1KDRSRPK2 | |
| SCHEMBL6000093 | 0.88 | SLC34A2 (0.54) | SLC34A2BRAFRAF1KDRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2590656-B1 | COMPOUNDS AND METHODS FOR INHIBITING PHOSPHATE TRANSPORT | ARDELYX INC (US) | 2017-11-15 | — | — | EP | claimed |