Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC34A2 | O95436 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 10/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.40 |
| ▸ | KDM1A | O60341 | 4/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.35 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.35 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.35 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.35 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.35 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.35 |
| ▸ | SMYD2 | Q9NRG4 | 2/20 | 0.35 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.34 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 4/20 | 0.34 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19580036 | 0.93 | SLC34A2 (0.48) | SLC34A2HDAC1KDM1ASMYD2ROCK2 | |
| SCHEMBL19579962 | 0.92 | SLC34A2 (0.48) | SLC34A2HDAC1KDM1AROCK2ROCK1 | |
| SCHEMBL19579947 | 0.91 | SLC34A2 (0.53) | SLC34A2HDAC1KDM1ASMYD2ROCK2 | |
| SCHEMBL19580004 | 0.91 | SLC34A2 (0.52) | SLC34A2HDAC1KDM1AROCK2ROCK1 | |
| SCHEMBL19579952 | 0.90 | SLC34A2 (0.49) | SLC34A2HDAC1KDM1AROCK2ROCK1 | |
| SCHEMBL19579978 | 0.90 | SLC34A2 (0.51) | SLC34A2HDAC1KDM1AROCK2ROCK1 | |
| SCHEMBL19580022 | 0.89 | SLC34A2 (0.50) | SLC34A2HDAC1KDM1AROCK2ROCK1 | |
| SCHEMBL19595685 | 0.89 | SLC34A2 (0.46) | SLC34A2HDAC1 | |
| SCHEMBL19579983 | 0.89 | SLC34A2 (0.46) | SLC34A2 | |
| SCHEMBL19579973 | 0.88 | SLC34A2 (0.53) | SLC34A2HDAC1KDM1ASMYD2ROCK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2590656-B1 | COMPOUNDS AND METHODS FOR INHIBITING PHOSPHATE TRANSPORT | ARDELYX INC (US) | 2017-11-15 | — | — | EP | claimed |