SCHEMBL19584783

SCHEMBL19584783

C[C@]12CCC(=O)C[C@@H]1CC[C@@H]1[C@@H]2CC[C@]2(C)[C@@H](C(=O)CO)CC[C@@H]12

nearest known ligand 0.76

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AKR1B10 O60218 3/20 0.76
AKR1B1 P15121 3/20 0.76
GPBAR1 Q8TDU6 3/20 0.76
CYP3A4 P08684 3/20 0.66
SHBG P04278 3/20 0.66
CYP19A1 P11511 2/20 0.66
SERPINA6 P08185 2/20 0.66
HSD17B10 Q99714 2/20 0.66
NR3C1 P04150 1/20 0.66
PGR P06401 1/20 0.66
NR3C2 P08235 1/20 0.66
AR P10275 1/20 0.66
MGAM O43451 1/20 0.66
G6PD P11413 6/20 0.65
ALDH1A1 P00352 3/20 0.65
KMT2A Q03164 2/20 0.65
MAPT P10636 2/20 0.65
CYP1A2 P05177 1/20 0.65
CYP2C9 P11712 1/20 0.65
TSHR P16473 1/20 0.65

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9510938 1.00 AKR1B10 (0.76) AKR1B10AKR1B1GPBAR1CYP3A4SHBG
SCHEMBL23144727 1.00 AKR1B10 (0.76) AKR1B10AKR1B1GPBAR1CYP3A4SHBG
SCHEMBL676328 1.00 AKR1B10 (0.76) AKR1B10AKR1B1GPBAR1CYP3A4SHBG
SCHEMBL144878 1.00 AKR1B10 (0.76) AKR1B10AKR1B1GPBAR1CYP3A4SHBG
SCHEMBL37778 0.86 AKR1B10 (1.00) AKR1B10AKR1B1GPBAR1CYP3A4SHBG
SCHEMBL675417 0.86 AKR1B10 (1.00) AKR1B10AKR1B1GPBAR1CYP3A4SHBG
SCHEMBL17776486 0.86 AKR1B10 (1.00) AKR1B10AKR1B1GPBAR1CYP3A4SHBG
SCHEMBL12646116 0.86 AKR1B10 (1.00) AKR1B10AKR1B1GPBAR1CYP3A4SHBG
SCHEMBL23699767 0.86 AKR1B10 (1.00) AKR1B10AKR1B1GPBAR1CYP3A4SHBG
SCHEMBL19156379 0.86 AKR1B10 (1.00) AKR1B10AKR1B1GPBAR1CYP3A4SHBG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 87 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240358719-A1 Formulations for Prolonging Gestation and for Complications of Menstruation or Gestation THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2024-10-31 US claimed
EP-4337234-A1 MICROBIOME MICROORGANISM AND USES THEREOF Biomica Ltd. (IL) 2024-03-20 EP claimed
EP-4313061-A1 FORMULATIONS FOR PROLONGING GESTATION AND FOR COMPLICATIONS OF MENSTRUATION OR GESTATION The Board of Trustees of the Leland Stanford Junior University (US) 2024-02-07 EP claimed
CN-117396597-A Microbiome microorganisms and uses thereof 生物米卡有限公司 2024-01-12 CN claimed
CN-117202910-A Formulations for prolonging pregnancy and for menstruation or pregnancy complications 斯坦福大学托管董事会 2023-12-08 CN claimed
WO-2022239013-A1 MICROBIOME MICROORGANISM AND USES THEREOF BIOMICA LTD. (IL) 2022-11-17 WO claimed
US-20220339176-A1 Methods of Treatments to Prolong Gestation and Complications of Menstruation or Gestation THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2022-10-27 US claimed
WO-2022211810-A1 FORMULATIONS FOR PROLONGING GESTATION AND FOR COMPLICATIONS OF MENSTRUATION OR GESTATION THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2022-10-06 WO claimed
EP-4034129-A1 METHODS OF TREATMENTS TO PROLONG GESTATION AND COMPLICATIONS OF MENSTRUATION OR GESTATION The Board of Trustees of the Leland Stanford Junior University (US) 2022-08-03 EP claimed
CN-114728013-A Methods of treating prolonged pregnancy and complications of menstruation or pregnancy 斯坦福大学托管董事会 2022-07-08 CN claimed
WO-2026076495-A1 METHOD OF TREATMENT OR INHIBITION TRKB Investments Pty Ltd (AU) 2026-04-16 WO disclosed
US-20260021111-A1 GANAXOLONE FOR USE IN TREATMENT OF STATUS EPILEPTICUS IMMEDICA PHARMA US INC (US) 2026-01-22 US disclosed
US-12504405-B2 Evaporation-based sample preparation workflow for mass spectrometry ROCHE DIAGNOSTICS OPERATIONS, INC. (US) 2025-12-23 US disclosed
US-20250152601-A1 Compositions and Methods for the Treatment of Sexual Dysfunctions THE JONATHAN HURT LIVING TRUST (US) 2025-05-15 US disclosed
US-12246026-B2 Ganaxolone for use in treatment of status epilepticus MARINUS PHARMACEUTICALS, INC. (US) 2025-03-11 US disclosed
US-20180050107-A1 NEUROSTEROID COMPOSITIONS AND METHODS OF USE THEREOF JANSSEN PHARMACEUTICA NV (BE) 2018-02-22 US disclosed
WO-2018022668-A2 NEUROMODULATING COMPOSITIONS AND RELATED THERAPEUTIC METHODS FOR THE TREATMENT OF CANCER FLAGSHIP PIONEERING, INC. (US) 2018-02-01 WO disclosed
WO-2018022664-A1 NEUROMODULATING COMPOSITIONS AND RELATED THERAPEUTIC METHODS FOR THE TREATMENT OF INFLAMMATORY AND AUTOIMMUNE DISEASES FLAGSHIP PIONEERING, INC. (US) 2018-02-01 WO disclosed
WO-2018022666-A1 NEUROMODULATING COMPOSITIONS AND RELATED THERAPEUTIC METHODS FOR THE TREATMENT OF CANCER BY MODULATING AN ANTI-CANCER IMMUNE RESPONSE FLAGSHIP PIONEERING, INC. (US) 2018-02-01 WO disclosed
WO-2017194748-A1 MEDICAMENT FOR TREATMENT AND/OR PROPHYLACTIC TREATMENT OF BREAST CANCER HAKMED AB (SE) 2017-11-16 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220339176-A1 Methods of Treatments to Prolong Gestation and Complications of Menstruation or Gestation PGF, GNRHR, PTGDR AKR1B10 1539/4885AKR1B1 1206/4885GPBAR1 217/4885
US-12246026-B2 Ganaxolone for use in treatment of status epilepticus CYP21A2, CYP17A1, HSD17B11 AKR1B10 559/4885AKR1B1 771/4885GPBAR1 600/4885
US-20260021111-A1 GANAXOLONE FOR USE IN TREATMENT OF STATUS EPILEPTICUS CYP4A11, CYP21A2, CYP17A1 AKR1B10 901/4885AKR1B1 1735/4885GPBAR1 704/4885
US-20240358719-A1 Formulations for Prolonging Gestation and for Complications of Menstruation or Gestation PGF, GNRHR, PTGDR AKR1B10 1173/4885AKR1B1 839/4885GPBAR1 145/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.