Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PER2 | O15055 | 6/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | AR | P10275 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | FABP4 | P15090 | 3/20 | 0.46 |
| ▸ | FABP5 | Q01469 | 3/20 | 0.46 |
| ▸ | FABP3 | P05413 | 1/20 | 0.46 |
| ▸ | TSPO | P30536 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18715068 | 1.00 | PER2 (0.49) | PER2KDM4EARPOLBFABP4 | |
| SCHEMBL1128885 | 0.80 | CYP1A2 (0.52) | PER2KDM4EFABP4FABP5FABP3 | |
| SCHEMBL26309809 | 0.75 | CYP1A2 (0.56) | PER2KDM4EFABP4FABP5FABP3 | |
| SCHEMBL13111957 | 0.75 | CYP1A2 (0.56) | PER2KDM4EPOLBFABP4FABP5 | |
| SCHEMBL18539423 | 0.73 | CYP1A2 (0.48) | PER2KDM4EFABP4FABP5FABP3 | |
| SCHEMBL1128466 | 0.72 | KDM4E (0.68) | KDM4EPOLBFABP4FABP5FABP3 | |
| SCHEMBL5186287 | 0.71 | PSEN1 (0.45) | KDM4EPOLBTSPOCYP1A2CYP2C19 | |
| SCHEMBL27622802 | 0.71 | POLB (0.53) | PER2KDM4EPOLBFABP4FABP5 | |
| SCHEMBL12386908 | 0.71 | CYP1A2 (0.50) | PER2KDM4EPOLBTSPOCYP1A2 | |
| SCHEMBL14421423 | 0.69 | FABP4 (0.70) | KDM4EPOLBFABP4FABP5FABP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9814698-B2 | Selective androgen receptor degrader (SARD) ligands and methods of use thereof | UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) | 2017-11-14 | — | — | US | disclosed |