Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.61 |
| ▸ | CA2 | P00918 | 3/20 | 0.61 |
| ▸ | TP53 | P04637 | 2/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.48 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.48 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.48 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10113658 | 0.90 | CA1 (0.77) | CA1CA2TP53L3MBTL1MEN1 | |
| SCHEMBL10112977 | 0.78 | DHFR (0.72) | CA1CA2L3MBTL1KMT2AALDH1A1 | |
| SCHEMBL3395610 | 0.77 | KIF11 (0.75) | TP53L3MBTL1NPSR1ALDH1A1 | |
| SCHEMBL19752619 | 0.77 | KIF11 (0.75) | TP53L3MBTL1NPSR1ALDH1A1 | |
| SCHEMBL10113582 | 0.76 | CA1 (0.67) | CA1CA2MEN1KMT2AALDH1A1 | |
| SCHEMBL17323002 | 0.76 | KIF11 (0.77) | NPSR1ALDH1A1KDM4EHSD17B10PKM | |
| SCHEMBL3329091 | 0.75 | TP53 (0.62) | TP53L3MBTL1MEN1KMT2AALDH1A1 | |
| SCHEMBL16366980 | 0.74 | CA1 (1.00) | CA1CA2MEN1KMT2AALDH1A1 | |
| SCHEMBL10112742 | 0.74 | ALDH1A1 (0.58) | CA1CA2KMT2ANPSR1ALDH1A1 | |
| SCHEMBL10113026 | 0.74 | DHFR (0.62) | CA1CA2TP53L3MBTL1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9815838-B2 | Methods and compositions for treating pain | HYDRA BIOSCIENCES, INC. (US) | 2017-11-14 | — | — | US | disclosed |