Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 5/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22105261 | 0.80 | PSEN1 (0.41) | THRBRAB9ALMNAHTTNPC1 | |
| SCHEMBL19590937 | 0.78 | ALDH1A1 (0.50) | LMNAMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL19590972 | 0.77 | MEN1 (0.47) | THRBRAB9ALMNAMEN1KMT2A | |
| SCHEMBL10114463 | 0.77 | TSHR (0.67) | THRBRAB9ALMNAHTTKMT2A | |
| SCHEMBL19590943 | 0.74 | GAA (0.45) | LMNAALDH1A1SMN1; SMN2GAAHPGD | |
| SCHEMBL19590970 | 0.74 | SMN1; SMN2 (0.44) | LMNAMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL19626687 | 0.73 | SMN1; SMN2 (0.42) | THRBRAB9ALMNAHTTNPC1 | |
| SCHEMBL19590909 | 0.73 | KMT2A (0.47) | LMNAMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL20290287 | 0.72 | POLB (0.51) | RAB9ALMNAHTTNPC1MEN1 | |
| SCHEMBL23416897 | 0.71 | CYP1A2 (0.42) | RAB9ALMNAHTTNPC1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9815838-B2 | Methods and compositions for treating pain | HYDRA BIOSCIENCES, INC. (US) | 2017-11-14 | — | — | US | disclosed |