Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19590966 | 0.82 | ALDH1A1 (0.51) | KMT2APOLBALDH1A1KDM4EMAPT | |
| SCHEMBL19590909 | 0.79 | KMT2A (0.47) | MEN1KMT2ATSHRSMN1; SMN2ALDH1A1 | |
| SCHEMBL20290287 | 0.78 | POLB (0.51) | MEN1KMT2ASMN1; SMN2POLBALDH1A1 | |
| SCHEMBL19997366 | 0.78 | POLB (0.46) | SMN1; SMN2POLBALDH1A1KDM4EHPGD | |
| SCHEMBL19590945 | 0.77 | THRB (0.46) | MEN1KMT2ATSHRSMN1; SMN2ALDH1A1 | |
| SCHEMBL22085071 | 0.77 | SMN1; SMN2 (0.46) | MEN1KMT2ATSHRSMN1; SMN2POLB | |
| SCHEMBL22105261 | 0.77 | PSEN1 (0.41) | MEN1KMT2ASMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL20079712 | 0.75 | TDP1 (0.47) | MEN1KMT2APOLBALDH1A1KDM4E | |
| SCHEMBL22105260 | 0.75 | KMT2A (0.46) | MEN1KMT2ASMN1; SMN2POLBALDH1A1 | |
| SCHEMBL10114522 | 0.73 | ALOX15 (0.78) | KMT2ATSHRPOLBALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9815838-B2 | Methods and compositions for treating pain | HYDRA BIOSCIENCES, INC. (US) | 2017-11-14 | — | — | US | disclosed |