Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23416909 | 0.76 | PORCN (0.58) | CYP1A2CYP2D6 | |
| SCHEMBL10114441 | 0.75 | ALDH1A1 (0.76) | SMN1; SMN2ALDH1A1NPSR1TP53CYP1A2 | |
| SCHEMBL23974592 | 0.74 | TSHR (0.57) | SMN1; SMN2ALDH1A1HPGDGAAPOLB | |
| SCHEMBL23416897 | 0.74 | CYP1A2 (0.42) | SMN1; SMN2ALDH1A1CYP2C9HPGDCYP2C19 | |
| SCHEMBL19626552 | 0.73 | TRPA1 (0.38) | SMN1; SMN2ALDH1A1NPSR1HPGDKDM4E | |
| SCHEMBL19590937 | 0.73 | ALDH1A1 (0.50) | SMN1; SMN2ALDH1A1CYP2C9HPGDCYP2C19 | |
| SCHEMBL19626687 | 0.72 | SMN1; SMN2 (0.42) | SMN1; SMN2ALDH1A1HPGDCYP1A2POLB | |
| SCHEMBL19036650 | 0.72 | YTHDC1 (0.43) | SMN1; SMN2ALDH1A1NPSR1CYP2C9HPGD | |
| SCHEMBL21935695 | 0.71 | PORCN (0.46) | SMN1; SMN2TP53 | |
| SCHEMBL22085071 | 0.71 | SMN1; SMN2 (0.46) | SMN1; SMN2ALDH1A1NPSR1POLBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9815838-B2 | Methods and compositions for treating pain | HYDRA BIOSCIENCES, INC. (US) | 2017-11-14 | — | — | US | disclosed |