Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 1/20 | 0.40 |
| ▸ | CHRNA5 | P30532 | 1/20 | 0.40 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.40 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HTR6 | P50406 | 2/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13265145 | 0.73 | POLB (0.45) | CHRNB2CHRNA5CHRNB4CHRNA3POLB | |
| SCHEMBL9520411 | 0.70 | POLB (0.49) | CHRNB4CHRNA3POLBHTR6 | |
| SCHEMBL10132336 | 0.69 | POLB (0.61) | CHRNB2POLBHTR6 | |
| SCHEMBL19654759 | 0.69 | POLB (0.61) | CHRNB2POLBHTR6 | |
| SCHEMBL3346478 | 0.68 | POLB (0.59) | CHRNB2CHRNA5CHRNB4CHRNA3POLB | |
| SCHEMBL3352624 | 0.68 | POLB (0.59) | CHRNB2CHRNA5CHRNB4CHRNA3POLB | |
| SCHEMBL6800803 | 0.68 | HTR6 (0.46) | POLBHTR6 | |
| SCHEMBL2712572 | 0.68 | POLB (0.58) | POLBHTR6 | |
| SCHEMBL23528204 | 0.67 | POLB (0.49) | CHRNB2CHRNA5CHRNB4CHRNA3POLB | |
| SCHEMBL3161248 | 0.66 | CHRNB2 (0.46) | CHRNB2CHRNA5CHRNB4CHRNA3POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9815814-B2 | Glutarimide derivatives, use thereof, pharmaceutical composition based thereon and methods for producing glutarimide derivatives | Obschestvo S Ogranichennoi Otvetstvennostiyu “Pharmenterprises” (RU) | 2017-11-14 | — | — | US | disclosed |