SCHEMBL19590974

SCHEMBL19590974

O=C1CCCC(O)N1CCc1cccnn1

nearest known ligand 0.35

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
HCRTR1 O43613 9/20 0.35
HCRTR2 O43614 9/20 0.35
CYP1A2 P05177 1/20 0.33
PER2 O15055 1/20 0.33
ADORA2B P29275 1/20 0.33
CTDSP1 Q9GZU7 1/20 0.32
CHRM2 P08172 1/20 0.31
CHRM4 P08173 1/20 0.31
CHRM1 P11229 1/20 0.31
CHRM3 P20309 1/20 0.31
VNN1 O95497 1/20 0.31
HRH3 Q9Y5N1 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17525626 0.76 HSD17B10 (0.39) CYP1A2CTDSP1
SCHEMBL19793343 0.75 HCRTR2 (0.36) HCRTR1HCRTR2
SCHEMBL19780652 0.73 NPC1 (0.38) HCRTR1HCRTR2
SCHEMBL19793300 0.73 KDM4E (0.34) HCRTR1HCRTR2
SCHEMBL20880132 0.70 TERT (0.39)
SCHEMBL22538918 0.70 FDPS (0.35) HCRTR1HCRTR2CHRM2CHRM1CHRM3
SCHEMBL25615350 0.70
SCHEMBL20880100 0.68 HCRTR1 (0.53) HCRTR1HCRTR2
SCHEMBL22538976 0.68 EPHX1 (0.40) HCRTR1HCRTR2HRH3
SCHEMBL19793288 0.68 HDAC1 (0.44) PER2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9815814-B2 Glutarimide derivatives, use thereof, pharmaceutical composition based thereon and methods for producing glutarimide derivatives Obschestvo S Ogranichennoi Otvetstvennostiyu “Pharmenterprises” (RU) 2017-11-14 US disclosed