Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 2/20 | 0.53 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 7/20 | 0.44 |
| ▸ | HTR1A | P08908 | 6/20 | 0.44 |
| ▸ | HTR7 | P34969 | 5/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 6/20 | 0.43 |
| ▸ | DRD4 | P21917 | 4/20 | 0.43 |
| ▸ | HTR2C | P28335 | 4/20 | 0.42 |
| ▸ | HRH1 | P35367 | 4/20 | 0.42 |
| ▸ | HTR2B | P41595 | 3/20 | 0.42 |
| ▸ | HTR2A | P28223 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17525605 | 0.79 | HTR1A (0.50) | HCRTR1HCRTR2ALOX15HTTSMN1; SMN2 | |
| SCHEMBL20880130 | 0.79 | HTR1A (0.50) | HCRTR1HCRTR2ALOX15HTTSMN1; SMN2 | |
| SCHEMBL22538918 | 0.72 | FDPS (0.35) | HCRTR1HCRTR2ALDH1A1MAPT | |
| SCHEMBL24691383 | 0.70 | DRD2 (0.59) | DRD2HTR1AHTR7SLC6A4DRD3 | |
| SCHEMBL17500049 | 0.70 | HTR1A (0.47) | ALOX15HTTSMN1; SMN2DRD2HTR1A | |
| SCHEMBL15238464 | 0.69 | HCRTR2 (1.00) | HCRTR1HCRTR2 | |
| SCHEMBL3919004 | 0.69 | UBE2T (0.61) | ALOX15HTTSMN1; SMN2L3MBTL1HPGD | |
| SCHEMBL19372016 | 0.68 | UBE2T (0.70) | ALOX15HTTSMN1; SMN2DRD2HTR1A | |
| SCHEMBL22144448 | 0.68 | HCRTR1 (0.44) | HCRTR1HCRTR2ALOX15HTTSMN1; SMN2 | |
| SCHEMBL22538944 | 0.68 | HRH3 (0.52) | HCRTR1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3466425-A1 | PHARMACEUTICAL COMPOSITION COMPRISING GLUTARIMIDE DERIVATIVES AND USE THEREOF IN THE TREATMENT OF EOSINOPHILIC DISEASES | Obschestvo S Ogranichennoi Otvetstvennostiyu "Pharmenterprises" (RU) | 2019-04-10 | — | — | EP | disclosed |