SCHEMBL19592001

SCHEMBL19592001

COP(=O)(O)OP(=O)(O)OP(=O)(O)OC[C@H]1O[C@@H](n2c[n+](C)c3c(=O)[nH]c(N)nc32)[C@@H](O)C1O

nearest known ligand 0.57

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
P2RY2 P41231 8/20 0.57
P2RY4 P51582 5/20 0.57
TGM2 P21980 1/20 0.56
P2RY14 Q15391 2/20 0.55
FUT5 Q11128 1/20 0.54
KRAS P01116 2/20 0.53
NT5E P21589 1/20 0.51
DCPS Q96C86 1/20 0.51
P2RY6 Q15077 6/20 0.51
P2RX3 P56373 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18769341 0.97 TGM2 (0.59) P2RY2P2RY4TGM2FUT5KRAS
SCHEMBL18769111 0.97 TGM2 (0.59) P2RY2P2RY4TGM2FUT5KRAS
SCHEMBL18769512 0.97 TGM2 (0.59) P2RY2P2RY4TGM2FUT5KRAS
SCHEMBL18769515 0.96 TGM2 (0.54) P2RY2P2RY4TGM2P2RY14FUT5
SCHEMBL20597816 0.94 TGM2 (0.57) P2RY2P2RY4TGM2FUT5KRAS
SCHEMBL17586590 0.94 TGM2 (0.57) P2RY2P2RY4TGM2FUT5KRAS
SCHEMBL23754698 0.93 TGM2 (0.57) P2RY2P2RY4TGM2FUT5KRAS
SCHEMBL21010336 0.93 TGM2 (0.57) P2RY2P2RY4TGM2FUT5KRAS
SCHEMBL18769054 0.93 TGM2 (0.54) P2RY2P2RY4TGM2FUT5KRAS
SCHEMBL2223109 0.93 TGM2 (0.57) P2RY2P2RY4TGM2FUT5KRAS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9814760-B2 Modified polynucleotides for the production of biologics and proteins associated with human disease MODERNATX, INC. (US) 2017-11-14 US disclosed