SCHEMBL23754698

SCHEMBL23754698

C[n+]1cn([C@@H]2O[C@H](COP(=O)(O)OP(=O)(O)O)[C@@H](O)[C@H]2O)c2nc(N)[nH]c(=O)c21

nearest known ligand 0.57

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TGM2 P21980 1/20 0.57
FUT5 Q11128 1/20 0.54
P2RY2 P41231 8/20 0.53
P2RY6 Q15077 7/20 0.53
ENPP1 P22413 2/20 0.53
P2RY1 P47900 2/20 0.53
P2RY12 Q9H244 1/20 0.53
NT5E P21589 1/20 0.53
P2RX1 P51575 1/20 0.53
P2RX3 P56373 1/20 0.53
P2RY11 Q96G91 1/20 0.53
P2RX4 Q99571 1/20 0.53
KRAS P01116 2/20 0.52
DCPS Q96C86 1/20 0.52
P2RY4 P51582 4/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21010336 1.00 TGM2 (0.57) TGM2FUT5P2RY2P2RY6ENPP1
SCHEMBL20597816 0.99 TGM2 (0.57) TGM2FUT5P2RY2P2RY6ENPP1
SCHEMBL17586590 0.99 TGM2 (0.57) TGM2FUT5P2RY2P2RY6ENPP1
SCHEMBL18769111 0.96 TGM2 (0.59) TGM2FUT5P2RY2P2RY6P2RY1
SCHEMBL18769341 0.96 TGM2 (0.59) TGM2FUT5P2RY2P2RY6P2RY1
SCHEMBL18769512 0.96 TGM2 (0.59) TGM2FUT5P2RY2P2RY6P2RY1
SCHEMBL25433573 0.95 TGM2 (0.55) TGM2FUT5P2RY2P2RY6ENPP1
SCHEMBL18769344 0.94 TGM2 (0.57) TGM2FUT5P2RY2P2RY6NT5E
Ammonia Solution, Strong SCHEMBL22134216 0.94 DCPS (0.57) TGM2FUT5P2RY2P2RY6ENPP1
SCHEMBL19592001 0.93 P2RY2 (0.57) TGM2FUT5P2RY2P2RY6NT5E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260109727-A1 RNA CONSTRUCTS AND USES THEREOF BioNTech SE (DE) 2026-04-23 US disclosed
US-20260009026-A1 Capped RNA and Method for Producing Same, Apparatus for Producing Protein, and Method for Producing Protein JAPAN SCIENCE & TECH AGENCY (JP) 2026-01-08 US disclosed
WO-2025217207-A1 SYSTEMS AND METHODS FOR EVALUATION OF GASTROINTESTINAL DISEASE AND APPLICATIONS THEREOF THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2025-10-16 WO disclosed
US-20250215043-A1 RNA CAP ANALOGS AND METHODS OF USE MEDICI THERAPEUTICS, INC. 2025-07-03 US disclosed
CN-120092014-A RNA constructs and uses thereof 生物技术欧洲股份公司 2025-06-03 CN disclosed
US-20250171489-A1 COMPOSITIONS AND METHODS FOR SYNTHESIZING 5'-CAPPED RNAS TRILINK BIOTECHNOLOGIES, LLC (US) 2025-05-29 US disclosed
CN-119677859-A Capped RNA, method for producing same, device for producing protein, and method for producing protein 国立研究开发法人科学技术振兴机构 2025-03-21 CN disclosed
WO-2025053250-A1 METHOD FOR PRODUCING PROTEIN OR PEPTIDE, METHOD FOR PRODUCING 5'-CAPPED POLYNUCLEOTIDE, AND REAGENT FOR USE IN SAID PRODUCTION METHODS 国立大学法人東海国立大学機構 2025-03-13 WO disclosed
EP-4509608-A1 CAPPED RNA AND METHOD FOR PRODUCING SAME, APPARATUS FOR PRODUCING PROTEIN, AND METHOD FOR PRODUCING PROTEIN Japan Science and Technology Agency (JP) 2025-02-19 EP disclosed
EP-4469465-A1 TRINUCLEOTIDE CAP ANALOGS AND METHODS OF USE THEREOF TriLink BioTechnologies, LLC (US) 2024-12-04 EP disclosed
WO-2023147352-A1 TRINUCLEOTIDE CAP ANALOGS AND METHODS OF USE THEREOF TRILINK BIOTECHNOLOGIES, LLC (US) 2023-08-03 WO disclosed
US-20230130423-A1 NOVEL MRNA 5'-END CAP ANALOGS, RNA MOLECULE INCORPORATING THE SAME, USES THEREOF AND METHOD OF SYNTHESIZING RNA MOLECULE OR PEPTIDE UNIWERSYTET WARSZAWSKI (PL) 2023-04-27 US disclosed
CN-115768437-A Capping compounds, compositions and methods of use thereof 磨石生物公司 2023-03-07 CN disclosed
WO-2023025073-A1 CAPPED ANALOG AND USE THEREOF 上海兆维科技发展有限公司 2023-03-02 WO disclosed
EP-4138854-A2 CAPPING COMPOUNDS, COMPOSITIONS AND METHODS OF USE THEREOF Gritstone bio, Inc. (US) 2023-03-01 EP disclosed
WO-2023282245-A1 METHOD FOR PURIFYING NUCLEOTIDES, DEVICE FOR PURIFYING NUCLEOTIDES, HYDROPHOBIC REAGENT, AND HYDROPHOBIC SUBSTRATE 国立研究開発法人科学技術振興機構 2023-01-12 WO disclosed
EP-4103578-A1 NOVEL MRNA 5'-END CAP ANALOGS MODIFIED WITHIN PHOSPHATE RESIDUES, RNA MOLECULE INCORPORATING THE SAME, USES THEREOF AND METHOD OF SYNTHESIZING RNA MOLECULE OR PEPTIDE Uniwersytet Warszawski (PL) 2022-12-21 EP disclosed
EP-4103577-A1 NOVEL MRNA 5'-END CAP ANALOGS, RNA MOLECULE INCORPORATING THE SAME, USES THEREOF AND METHOD OF SYNTHESIZING RNA MOLECULE OR PEPTIDE Uniwersytet Warszawski (PL) 2022-12-21 EP disclosed
WO-2021162566-A1 NOVEL MRNA 5'-END CAP ANALOGS MODIFIED WITHIN PHOSPHATE RESIDUES, RNA MOLECULE INCORPORATING THE SAME, USES THEREOF AND METHOD OF SYNTHESIZING RNA MOLECULE OR PEPTIDE UNIWERSYTET WARSZAWSKI (PL) 2021-08-19 WO disclosed
WO-2021162567-A1 NOVEL MRNA 5'-END CAP ANALOGS, RNA MOLECULE INCORPORATING THE SAME, USES THEREOF AND METHOD OF SYNTHESIZING RNA MOLECULE OR PEPTIDE UNIWERSYTET WARSZAWSKI (PL) 2021-08-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230130423-A1 NOVEL MRNA 5'-END CAP ANALOGS, RNA MOLECULE INCORPORATING THE SAME, USES THEREOF AND METHOD OF SYNTHESIZING RNA MOLECULE OR PEPTIDE RNGTT, RNMT, NSUN3 TGM2 3118/4885FUT5 2895/4885P2RY2 4196/4885
US-20250215043-A1 RNA CAP ANALOGS AND METHODS OF USE RNGTT, RNMT, NSUN2 TGM2 3831/4885FUT5 1497/4885P2RY2 3925/4885
US-20250171489-A1 COMPOSITIONS AND METHODS FOR SYNTHESIZING 5'-CAPPED RNAS RNGTT, RNMT, NT5C3B TGM2 1420/4885FUT5 263/4885P2RY2 2018/4885
US-20260009026-A1 Capped RNA and Method for Producing Same, Apparatus for Producing Protein, and Method for Producing Protein RNGTT, RNMT, NSUN3 TGM2 3538/4885FUT5 3495/4885P2RY2 3331/4885
US-20260109727-A1 RNA CONSTRUCTS AND USES THEREOF RNGTT, RNMT, NSUN3 TGM2 2526/4885FUT5 1302/4885P2RY2 577/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.