Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 1/20 | 0.57 |
| ▸ | FUT5 | Q11128 | 1/20 | 0.55 |
| ▸ | P2RY2 | P41231 | 8/20 | 0.55 |
| ▸ | P2RY6 | Q15077 | 6/20 | 0.55 |
| ▸ | ENPP1 | P22413 | 2/20 | 0.54 |
| ▸ | P2RY1 | P47900 | 2/20 | 0.54 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.54 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.54 |
| ▸ | P2RY11 | Q96G91 | 1/20 | 0.54 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.54 |
| ▸ | KRAS | P01116 | 2/20 | 0.54 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.53 |
| ▸ | P2RY4 | P51582 | 4/20 | 0.52 |
| ▸ | NT5E | P21589 | 1/20 | 0.52 |
| ▸ | DCPS | Q96C86 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20597816 | 1.00 | TGM2 (0.57) | TGM2FUT5P2RY2P2RY6ENPP1 | |
| SCHEMBL21010336 | 0.99 | TGM2 (0.57) | TGM2FUT5P2RY2P2RY6ENPP1 | |
| SCHEMBL23754698 | 0.99 | TGM2 (0.57) | TGM2FUT5P2RY2P2RY6ENPP1 | |
| SCHEMBL18769111 | 0.97 | TGM2 (0.59) | TGM2FUT5P2RY2P2RY6P2RY1 | |
| SCHEMBL18769512 | 0.97 | TGM2 (0.59) | TGM2FUT5P2RY2P2RY6P2RY1 | |
| SCHEMBL18769341 | 0.97 | TGM2 (0.59) | TGM2FUT5P2RY2P2RY6P2RY1 | |
| SCHEMBL25433573 | 0.94 | TGM2 (0.55) | TGM2FUT5P2RY2P2RY6ENPP1 | |
| SCHEMBL19592001 | 0.94 | P2RY2 (0.57) | TGM2FUT5P2RY2P2RY6P2RX3 | |
| SCHEMBL2223109 | 0.93 | TGM2 (0.57) | TGM2FUT5P2RY2P2RY6P2RX3 | |
| SCHEMBL18769344 | 0.93 | TGM2 (0.57) | TGM2FUT5P2RY2P2RY6P2RX3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160075733-A1 | MODIFIED POLYNUCLEOTIDES FOR THE PRODUCTION OF BIOLOGICS AND PROTEINS ASSOCIATED WITH HUMAN DISEASE | ARES CAPITAL CORPORATION, AS AGENT | 2016-03-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160075733-A1 | MODIFIED POLYNUCLEOTIDES FOR THE PRODUCTION OF BIOLOGICS AND PROTEINS ASSOCIATED WITH HUMAN DISEASE | POLRMT, POLN, POLM | TGM2 3805/4885FUT5 2012/4885P2RY2 2758/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.