Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | ACACB | O00763 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19299700 | 0.85 | ALDH1A1 (0.57) | MEN1KMT2AMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL12697080 | 0.80 | KDM4E (0.74) | MEN1KMT2AMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL19299702 | 0.74 | MAPT (0.54) | KMT2AMAPTALDH1A1HPGDPOLB | |
| SCHEMBL21416869 | 0.72 | RAB9A (0.47) | KMT2AALDH1A1SMN1; SMN2HPGDKDM4E | |
| SCHEMBL8241785 | 0.69 | RAB9A (0.66) | KMT2AMAPTALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL1106975 | 0.69 | KMT2A (0.62) | KMT2AMAPTALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL19294525 | 0.68 | RECQL (0.55) | MEN1KMT2AALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL12591803 | 0.68 | KMT2A (0.63) | KMT2AMAPTALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL19299646 | 0.68 | UBE2N (0.59) | MEN1KMT2AMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL8430118 | 0.68 | RAB9A (0.68) | KMT2AMAPTALDH1A1SMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3243513-A1 | USE OF THE RNASE INHIBITOR RNPA-3000 FOR TREATING STAPHYLOCOCCUS INFECTIONS | University Of Rochester (US) | 2017-11-15 | — | — | EP | disclosed |