Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB11 | O95342 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.31 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.31 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8745522 | 0.86 | CA2 (0.34) | — | |
| SCHEMBL8395168 | 0.80 | CYP2C19 (0.39) | — | |
| SCHEMBL9574397 | 0.74 | ALOX15 (0.39) | — | |
| SCHEMBL28102916 | 0.74 | CA2 (0.34) | CYP3A4KDM4ERECQL | |
| SCHEMBL23568387 | 0.73 | KDM4E (0.47) | ABCB11CYP3A4ADRA2BOPRD1SCN5A | |
| SCHEMBL15114177 | 0.73 | KDM4E (0.47) | ABCB11CYP3A4ADRA2BOPRD1SCN5A | |
| SCHEMBL10350619 | 0.73 | KDM4E (0.47) | ABCB11CYP3A4ADRA2BOPRD1SCN5A | |
| SCHEMBL15025288 | 0.73 | KDM4E (0.47) | ABCB11CYP3A4ADRA2BOPRD1SCN5A | |
| SCHEMBL22856505 | 0.73 | KDM4E (0.47) | ABCB11CYP3A4ADRA2BOPRD1SCN5A | |
| SCHEMBL2090757 | 0.73 | PIK3CD (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2590656-B1 | COMPOUNDS AND METHODS FOR INHIBITING PHOSPHATE TRANSPORT | ARDELYX INC (US) | 2017-11-15 | — | — | EP | disclosed |