Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | THRA | P10827 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2498188 | 0.95 | ALOX15 (0.41) | ALOX15ALDH1A1TSHRTHRATHRB | |
| SCHEMBL11372483 | 0.89 | ALOX15 (0.38) | ALOX15ALDH1A1TSHR | |
| SCHEMBL616451 | 0.88 | ALOX15 (0.44) | ALOX15ALDH1A1TSHRTHRA | |
| SCHEMBL2500023 | 0.84 | ADH1A (0.33) | ALOX15HSD17B10 | |
| SCHEMBL23085416 | 0.83 | ALOX15 (0.34) | ALOX15 | |
| SCHEMBL8745522 | 0.82 | CA2 (0.34) | BLMPMP22HSD17B10 | |
| SCHEMBL23085322 | 0.80 | ALOX15 (0.38) | ALOX15ALDH1A1TSHRTHRATHRB | |
| SCHEMBL4634763 | 0.80 | TSHR (0.43) | ALDH1A1TSHRTHRB | |
| SCHEMBL11371637 | 0.79 | MEN1 (0.37) | ALOX15 | |
| SCHEMBL770546 | 0.79 | CA12 (0.39) | ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0302441-B1 | BIS-STYRYL COMPOUNDS | BASF Aktiengesellschaft (DE) | 1993-05-12 | — | — | EP | disclosed |
| EP-0302441-A2 | Bis-styryl compounds | BASF Aktiengesellschaft (DE) | 1989-02-08 | — | — | EP | disclosed |