SCHEMBL19600432

SCHEMBL19600432

c1ccc(-c2cc(-c3ccccc3)cc(-c3ccc4c(c3)Oc3cccc5c(-c6ccc7ccc8cccc9ccc6c7c89)ccc-4c35)c2)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.44
MAPK1 P28482 1/20 0.44
ATM Q13315 1/20 0.44
CYP1A2 P05177 3/20 0.38
FYN P06241 2/20 0.38
AHR P35869 2/20 0.38
ERBB2 P04626 1/20 0.38
MAOA P21397 1/20 0.38
ACHE P22303 1/20 0.38
PGR P06401 1/20 0.34
ALDH1A1 P00352 2/20 0.33
HPGD P15428 2/20 0.33
HSD17B10 Q99714 2/20 0.33
THRB P10828 1/20 0.33
CYP19A1 P11511 1/20 0.33
GPR84 Q9NQS5 2/20 0.32
HSD17B1 P14061 1/20 0.32
HSD17B2 P37059 1/20 0.32
TYMS P04818 1/20 0.32
CYP1A1 P04798 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19600409 0.97 KDM4E (0.46) KDM4EMAPK1ATMCYP1A2FYN
SCHEMBL17265406 0.89 CYP1A2 (0.38) KDM4EMAPK1ATMCYP1A2FYN
SCHEMBL24810710 0.88 MAPK1 (0.51) KDM4EMAPK1ATMCYP1A2FYN
SCHEMBL19600435 0.86 MAPK1 (0.40) KDM4EMAPK1ATMCYP1A2FYN
SCHEMBL16558308 0.85 MAPK1 (0.58) KDM4EMAPK1ATMCYP1A2FYN
SCHEMBL19600415 0.85 KDM4E (0.43) KDM4EMAPK1ATMALDH1A1HPGD
SCHEMBL19600397 0.84 ATM (0.42) KDM4EMAPK1ATMMAOAHPGD
SCHEMBL16558307 0.84 MAPK1 (0.56) KDM4EMAPK1ATMCYP1A2FYN
SCHEMBL19600402 0.83 KDM4E (0.47) KDM4EMAPK1ATMCYP1A2ALDH1A1
SCHEMBL24923312 0.83 MAPK1 (0.55) KDM4EMAPK1ATMCYP1A2FYN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10573825-B2 Compound and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2020-02-25 US disclosed
US-20170331051-A1 COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2017-11-16 US disclosed
US-20170331051-A1 COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2017-11-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10573825-B2 Compound and organic light-emitting device including the same CRY1, CRY2, AOX1 KDM4E 2074/4885MAPK1 2174/4885ATM 2475/4885
US-20170331051-A1 COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME CRY1, CRY2, AOX1 KDM4E 2074/4885MAPK1 2174/4885ATM 2475/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.