SCHEMBL19600446

SCHEMBL19600446

Clc1ccc2c(c1)Oc1cccc3c(-c4cc5ccccc5c5c4oc4ccc6ccccc6c45)ccc-2c13

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.37
MAPK1 P28482 2/20 0.37
ATM Q13315 1/20 0.37
CYP1A1 P04798 6/20 0.33
CYP1A2 P05177 6/20 0.33
AHR P35869 6/20 0.33
KMT2A Q03164 2/20 0.33
FYN P06241 1/20 0.33
MAPK3 P27361 1/20 0.33
PAX8 Q06710 1/20 0.33
ABCG2 Q9UNQ0 1/20 0.33
CYP1B1 Q16678 5/20 0.32
ALDH1A1 P00352 1/20 0.31
HPGD P15428 1/20 0.31
TSHR P16473 1/20 0.31
CASP1 P29466 1/20 0.31
HIF1A Q16665 1/20 0.31
HSD17B10 Q99714 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
MAOA P21397 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19600447 0.89 KDM4E (0.35) KDM4EMAPK1ATMAHRKMT2A
SCHEMBL19600424 0.87 ABCG2 (0.38) KDM4EMAPK1ATMCYP1A1CYP1A2
SCHEMBL19600436 0.78 KDM4E (0.35) KDM4EMAPK1ATMCYP1A1CYP1A2
SCHEMBL17737554 0.77 MAPK1 (0.36) KDM4EMAPK1ATMCYP1A1CYP1A2
SCHEMBL19600445 0.76 MAPK1 (0.42) KDM4EMAPK1ATMCYP1A1CYP1A2
SCHEMBL19600411 0.76 MAPK1 (0.35) KDM4EMAPK1ATMCYP1A1CYP1A2
SCHEMBL24742252 0.72 MAPK1 (0.65) KDM4EMAPK1ATMAHRALDH1A1
SCHEMBL17702477 0.72 AHR (0.34) KDM4EMAPK1ATMCYP1A2AHR
SCHEMBL18471555 0.71 ABCG2 (0.50) KDM4EMAPK1CYP1A1CYP1A2AHR
SCHEMBL17737556 0.71 KDM4E (0.31) KDM4EMAPK1ATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10573825-B2 Compound and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2020-02-25 US disclosed
US-20170331051-A1 COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2017-11-16 US disclosed
US-20170331051-A1 COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2017-11-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10573825-B2 Compound and organic light-emitting device including the same CRY1, CRY2, AOX1 KDM4E 2074/4885MAPK1 2174/4885ATM 2475/4885
US-20170331051-A1 COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME CRY1, CRY2, AOX1 KDM4E 2074/4885MAPK1 2174/4885ATM 2475/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.