SCHEMBL19600562

SCHEMBL19600562

C[Si](C)(C)c1ccc(CCN)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 9/20 0.56
CYP2A6 P11509 2/20 0.56
CYP1A2 P05177 1/20 0.56
HTR2A P28223 4/20 0.50
LOXL2 Q9Y4K0 2/20 0.50
KDM4E B2RXH2 1/20 0.50
ALDH1A1 P00352 1/20 0.50
HTR1A P08908 1/20 0.50
ADRA2A P08913 1/20 0.50
SLC6A2 P23975 1/20 0.50
CYP2C19 P33261 1/20 0.50
HTR3A P46098 1/20 0.50
BACE1 P56817 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
BLM P54132 1/20 0.48
KMT2A Q03164 1/20 0.48
TDP1 Q9NUW8 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
MAOB P27338 3/20 0.45
NOS3 P29474 2/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6510336 0.85 ESR1 (0.41) TAAR1CYP2A6CYP1A2MAOB
SCHEMBL5470508 0.80 HRH3 (0.50) TAAR1LOXL2NOS3NOS1NOS2
SCHEMBL224548 0.79 TAAR1 (0.72) TAAR1CYP2A6CYP1A2HTR2ALOXL2
SCHEMBL3264156 0.78 LPL (0.46) KDM4EALDH1A1L3MBTL1
Ethane SCHEMBL9529291 0.78 HRH3 (0.48) TAAR1LOXL2NOS3NOS1NOS2
SCHEMBL27696536 0.76 MGAM (0.36) TAAR1CYP2A6CYP1A2
SCHEMBL6309545 0.76 CA2 (0.52) KDM4EALDH1A1BACE1TDP1
Hydrochloric Acid SCHEMBL3168355 0.76 BLM (0.74) TAAR1CYP2A6CYP1A2HTR2ALOXL2
Hydrochloric Acid SCHEMBL3668004 0.76 BLM (0.74) TAAR1CYP2A6CYP1A2HTR2ALOXL2
Iodide SCHEMBL29101247 0.76 TAAR1 (0.68) TAAR1CYP2A6CYP1A2HTR2ALOXL2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190304707-A1 PHOTOELECTRIC CONVERSION ELEMENT, SOLAR CELL AND COMPOSITION FUJIFILM CORPORATION (JP) 2019-10-03 US disclosed
US-10418186-B2 Photoelectric conversion element, solar cell and composition FUJIFILM CORPORATION (JP) 2019-09-17 US disclosed
US-20170330694-A1 PHOTOELECTRIC CONVERSION ELEMENT, SOLAR CELL AND COMPOSITION FUJIFILM CORPORATION (JP) 2017-11-16 US disclosed
US-20170330694-A1 PHOTOELECTRIC CONVERSION ELEMENT, SOLAR CELL AND COMPOSITION FUJIFILM CORPORATION (JP) 2017-11-16 US disclosed