Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.48 |
| ▸ | LOXL2 | Q9Y4K0 | 7/20 | 0.46 |
| ▸ | ABAT | P80404 | 1/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.41 |
| ▸ | NOS3 | P29474 | 2/20 | 0.40 |
| ▸ | NOS1 | P29475 | 2/20 | 0.40 |
| ▸ | NOS2 | P35228 | 2/20 | 0.40 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.40 |
| ▸ | F10 | P00742 | 1/20 | 0.38 |
| ▸ | F11 | P03951 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | CA6 | P23280 | 1/20 | 0.38 |
| ▸ | CA5A | P35218 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5470508 | 0.97 | HRH3 (0.50) | HRH3LOXL2ABATTAAR1NOS3 | |
| SCHEMBL10914886 | 0.82 | HRH3 (0.50) | HRH3LOXL2ABATTAAR1NOS3 | |
| SCHEMBL27786246 | 0.78 | HRH3 (0.46) | HRH3LOXL2ABATTAAR1NOS3 | |
| SCHEMBL27920384 | 0.78 | LOXL2 (0.48) | HRH3LOXL2ABATTAAR1NOS3 | |
| SCHEMBL15981407 | 0.78 | ABAT (0.48) | HRH3LOXL2ABATTAAR1NOS3 | |
| SCHEMBL19600562 | 0.78 | TAAR1 (0.56) | LOXL2TAAR1NOS3NOS1NOS2 | |
| SCHEMBL6510336 | 0.76 | ESR1 (0.41) | HRH3TAAR1 | |
| SCHEMBL1908526 | 0.75 | PNMT (0.48) | LOXL2NOS3NOS1NOS2 | |
| SCHEMBL15828 | 0.74 | HRH3 (0.79) | HRH3LOXL2ABATTAAR1NOS3 | |
| SCHEMBL586534 | 0.74 | NR1H2 (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0555388-A1 | INSECTICIDAL, ACARICIDAL AND FUNGICIDAL AMINOPYRIMIDINES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1993-08-18 | — | — | EP | disclosed |