Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.60 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.60 |
| ▸ | XDH | P47989 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | ALPG | P10696 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19600972 | 0.82 | HIF1A (0.41) | PTGS1PTGS2XDHMAPTGAA | |
| SCHEMBL30140565 | 0.80 | XDH (0.68) | PTGS1PTGS2XDHMAPTGAA | |
| SCHEMBL8723354 | 0.80 | XDH (0.68) | PTGS1PTGS2XDHMAPTGAA | |
| SCHEMBL11098662 | 0.76 | HTR2C (0.44) | PTGS1PTGS2XDHMAPTGAA | |
| Daedalin A SCHEMBL29983386 | 0.75 | PTGS1 (1.00) | PTGS1PTGS2XDHMAPTGAA | |
| Quercinol SCHEMBL29967584 | 0.74 | PTGS1 (0.60) | PTGS1PTGS2XDHMAPTGAA | |
| Cordiachromene A SCHEMBL16666262 | 0.68 | PTGS1 (0.68) | PTGS1PTGS2XDHMAPTGAA | |
| Cordiachromene A SCHEMBL9356402 | 0.68 | PTGS1 (0.68) | PTGS1PTGS2XDHMAPTGAA | |
| Cordiachromene A SCHEMBL16666288 | 0.68 | PTGS1 (0.68) | PTGS1PTGS2XDHMAPTGAA | |
| SCHEMBL31254058 | 0.66 | PTPN1 (0.52) | PTGS1PTGS2XDHMAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10376476-B2 | Panicein compounds, compositions and uses thereof | UNIVERSITE NICE SOPHIA ANTIPOLIS (FR) | 2019-08-13 | — | — | US | disclosed |
| US-20180200200-A1 | PANICEIN COMPOUNDS, COMPOSITIONS AND USES THEREOF | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2018-07-19 | — | — | US | disclosed |
| US-20180200200-A1 | PANICEIN COMPOUNDS, COMPOSITIONS AND USES THEREOF | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2018-07-19 | — | — | US | disclosed |
| US-20170326076-A1 | PANICEIN COMPOUNDS, COMPOSITIONS AND USES THEREOF | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2017-11-16 | — | — | US | disclosed |
| US-20170326076-A1 | PANICEIN COMPOUNDS, COMPOSITIONS AND USES THEREOF | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2017-11-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170326076-A1 | PANICEIN COMPOUNDS, COMPOSITIONS AND USES THEREOF | ABCC1, ABCB1, SLC47A1 | PTGS1 871/4885PTGS2 1253/4885XDH 2207/4885 |
| US-10376476-B2 | Panicein compounds, compositions and uses thereof | ABCC1, ABCB1, SLC47A1 | PTGS1 871/4885PTGS2 1253/4885XDH 2207/4885 |
| US-20180200200-A1 | PANICEIN COMPOUNDS, COMPOSITIONS AND USES THEREOF | ABCC1, ABCB1, SLC47A1 | PTGS1 871/4885PTGS2 1253/4885XDH 2207/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.