Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 2/20 | 0.68 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.68 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.68 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 2/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | ALPG | P10696 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | TYR | P14679 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30140565 | 1.00 | XDH (0.68) | XDHPTGS1PTGS2PTPN1TDP1 | |
| SCHEMBL31254058 | 0.85 | PTPN1 (0.52) | XDHPTGS1PTGS2PTPN1TDP1 | |
| SCHEMBL27810630 | 0.85 | PTPN1 (0.52) | XDHPTGS1PTGS2PTPN1TDP1 | |
| SCHEMBL14541271 | 0.81 | COXFA4 (0.52) | XDHPTGS1PTGS2PTPN1TDP1 | |
| Daedalin A SCHEMBL29983386 | 0.81 | PTGS1 (1.00) | XDHPTGS1PTGS2PTPN1TDP1 | |
| Quercinol SCHEMBL29967584 | 0.80 | PTGS1 (0.60) | XDHPTGS1PTGS2PTPN1TDP1 | |
| SCHEMBL19600968 | 0.80 | PTGS1 (0.60) | XDHPTGS1PTGS2PTPN1TDP1 | |
| SCHEMBL3049240 | 0.79 | ALDH1A1 (0.46) | XDHPTGS1PTGS2PTPN1TDP1 | |
| SCHEMBL7738844 | 0.79 | HIF1A (0.58) | XDHPTGS1PTGS2PTPN1TDP1 | |
| SCHEMBL6024450 | 0.78 | HTR2C (0.54) | XDHPTGS1PTGS2PTPN1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230165276-A1 | NOVEL USE OF SUBSTITUTED 2H-CHROMENS AND THEIR DERIVATIVES | DSM IP ASSETS B.V. (NL) | 2023-06-01 | — | — | US | disclosed |
| US-20230165276-A1 | NOVEL USE OF SUBSTITUTED 2H-CHROMENS AND THEIR DERIVATIVES | DSM IP ASSETS B.V. (NL) | 2023-06-01 | — | — | US | disclosed |
| US-20230165276-A1 | NOVEL USE OF SUBSTITUTED 2H-CHROMENS AND THEIR DERIVATIVES | DSM IP ASSETS B.V. (NL) | 2023-06-01 | — | — | US | disclosed |
| CN-115518096-A | Integrated comprehensive extraction and separation method for effective components of epimedium | 李玉山 | 2022-12-27 | — | — | CN | disclosed |
| EP-3818136-A1 | NOVEL USE OF SUBSTITUTED 2H-CHROMENS AND THEIR DERIVATIVES | DSM IP Assets B.V. (NL) | 2021-05-12 | — | — | EP | disclosed |
| WO-2021069752-A1 | NEW FEED ADDITIVES OF FAT-SOLUBLE VITAMINS | DSM IP ASSETS B.V. (NL) | 2021-04-15 | — | — | WO | disclosed |
| CN-111936483-A | Process for preparing chroman-6-ols having short side chains | 帝斯曼知识产权资产管理有限公司 | 2020-11-13 | — | — | CN | disclosed |
| WO-2019185910-A2 | NOVEL USE OF SUBSTITUTED 2H-CHROMENS AND THEIR DERIVATIVES | DSM IP ASSETS B.V. (NL) | 2019-10-03 | — | — | WO | disclosed |
| WO-2019185910-A2 | NOVEL USE OF SUBSTITUTED 2H-CHROMENS AND THEIR DERIVATIVES | DSM IP ASSETS B.V. (NL) | 2019-10-03 | — | — | WO | disclosed |
| WO-2019185898-A1 | NOVEL USE OF SUBSTITUTED 2H-CHROMENS AND THEIR DERIVATIVES | DSM IP ASSETS B.V. (NL) | 2019-10-03 | — | — | WO | disclosed |
| WO-2019185898-A1 | NOVEL USE OF SUBSTITUTED 2H-CHROMENS AND THEIR DERIVATIVES | DSM IP ASSETS B.V. (NL) | 2019-10-03 | — | — | WO | disclosed |
| US-20170326076-A1 | PANICEIN COMPOUNDS, COMPOSITIONS AND USES THEREOF | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2017-11-16 | — | — | US | disclosed |
| WO-1998034646-A2 | TARGETED ANTIOXIDANTS | UNIVERSITY OF HERTFORDSHIRE (GB) | 1998-08-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230165276-A1 | NOVEL USE OF SUBSTITUTED 2H-CHROMENS AND THEIR DERIVATIVES | CRY1, HRH3, CYP4F12 | XDH 2367/4885PTGS1 823/4885PTGS2 508/4885 |
| US-20170326076-A1 | PANICEIN COMPOUNDS, COMPOSITIONS AND USES THEREOF | ABCC1, ABCB1, SLC47A1 | XDH 2207/4885PTGS1 871/4885PTGS2 1253/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.