Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 3/20 | 0.38 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | HTR7 | P34969 | 1/20 | 0.32 |
| ▸ | HRH1 | P35367 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.32 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.31 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6955673 | 0.81 | MCHR1 (0.34) | MCHR1 | |
| SCHEMBL27561109 | 0.81 | MCHR1 (0.37) | MCHR1SRD5A1HTR1ADRD2HTR2A | |
| SCHEMBL19600978 | 0.79 | DRD2 (0.38) | MCHR1DRD2HTR2ADRD3 | |
| SCHEMBL19600975 | 0.78 | CYP11B1 (0.52) | MCHR1DRD2DRD3ALDH1A1 | |
| SCHEMBL6953646 | 0.77 | MCHR1 (0.45) | MCHR1ALDH1A1 | |
| SCHEMBL13239080 | 0.75 | SRD5A1 (0.37) | SRD5A1ALDH1A1PARP10PARP11 | |
| SCHEMBL11911369 | 0.73 | MCHR1 (0.42) | MCHR1ALDH1A1 | |
| SCHEMBL8099968 | 0.73 | MCHR1 (0.42) | MCHR1ALDH1A1 | |
| SCHEMBL6080770 | 0.73 | HTR2A (0.53) | HTR1ADRD2HTR2AHTR2CHTR7 | |
| SCHEMBL11811073 | 0.71 | MCHR1 (0.41) | MCHR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170327439-A1 | DIHYDRONAPHTHALENE DERIVATIVE | ONO PHARMACEUTICAL CO., LTD. (JP) | 2017-11-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170327439-A1 | DIHYDRONAPHTHALENE DERIVATIVE | S1PR5, LPAR5, S1PR1 | MCHR1 532/4885SRD5A1 536/4885HTR1A 73/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.