Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 9/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.40 |
| ▸ | PDE5A | O76074 | 1/20 | 0.39 |
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19601311 | 0.92 | TRPA1 (0.51) | TRPA1KMT2AADORA2BPDE5APDE4A | |
| SCHEMBL17682140 | 0.88 | TRPA1 (0.50) | TRPA1 | |
| SCHEMBL19601336 | 0.87 | ADORA2B (0.54) | ADORA2BPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL19601329 | 0.87 | ADORA2B (0.54) | ADORA2BPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL17682138 | 0.87 | ADORA2B (0.54) | ADORA2BPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL17682301 | 0.85 | TRPA1 (0.55) | TRPA1KMT2AADORA2BPDE5APDE4A | |
| SCHEMBL19601314 | 0.85 | LMNA (0.48) | TRPA1KMT2AADORA2BPDE5APDE4A | |
| SCHEMBL19601332 | 0.85 | LMNA (0.48) | TRPA1KMT2AADORA2BPDE5APDE4A | |
| SCHEMBL17682303 | 0.85 | TRPA1 (0.54) | TRPA1KMT2AADORA2BPDE5APDE4A | |
| SCHEMBL19601337 | 0.85 | LMNA (0.48) | TRPA1KMT2AADORA2BPDE5APDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170326149-A1 | HYDROXYL PURINE COMPOUNDS AND APPLICATIONS THEREOF | GUANGDONG ZHONGSHENG PHARMACEUTICAL CO., LTD (CN) | 2017-11-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170326149-A1 | HYDROXYL PURINE COMPOUNDS AND APPLICATIONS THEREOF | PNP, PDE2A, PDE7A | TRPA1 3239/4885KMT2A 3904/4885ADORA2B 116/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.