Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 2/20 | 0.36 |
| ▸ | PARG | Q86W56 | 8/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | PDE5A | O76074 | 2/20 | 0.32 |
| ▸ | PDE4A | P27815 | 2/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.32 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17682131 | 0.89 | TRPA1 (0.34) | TRPA1PARGLMNAALDH1A1POLB | |
| SCHEMBL17682319 | 0.85 | TRPA1 (0.36) | TRPA1PARGLMNAALDH1A1POLB | |
| SCHEMBL17682323 | 0.85 | TRPA1 (0.37) | TRPA1PARGLMNAPDE5APDE4A | |
| SCHEMBL19601311 | 0.83 | TRPA1 (0.51) | TRPA1PDE5APDE4APDE4BPDE4C | |
| SCHEMBL17682326 | 0.83 | TRPA1 (0.35) | TRPA1LMNAALDH1A1POLB | |
| SCHEMBL19601306 | 0.77 | TRPA1 (0.53) | TRPA1PDE5APDE4APDE4BPDE4C | |
| SCHEMBL19601329 | 0.73 | ADORA2B (0.54) | LMNAPOLBPDE4APDE4BPDE4C | |
| SCHEMBL19601336 | 0.73 | ADORA2B (0.54) | LMNAPOLBPDE4APDE4BPDE4C | |
| SCHEMBL17682138 | 0.73 | ADORA2B (0.54) | LMNAPOLBPDE4APDE4BPDE4C | |
| SCHEMBL17682130 | 0.72 | TRPA1 (0.48) | TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170326149-A1 | HYDROXYL PURINE COMPOUNDS AND APPLICATIONS THEREOF | GUANGDONG ZHONGSHENG PHARMACEUTICAL CO., LTD (CN) | 2017-11-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170326149-A1 | HYDROXYL PURINE COMPOUNDS AND APPLICATIONS THEREOF | PNP, PDE2A, PDE7A | TRPA1 3239/4885PARG 2420/4885LMNA 2616/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.