Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 10/20 | 0.81 |
| ▸ | NPC1 | O15118 | 9/20 | 0.81 |
| ▸ | POLB | P06746 | 2/20 | 0.81 |
| ▸ | MEN1 | O00255 | 2/20 | 0.81 |
| ▸ | LMNA | P02545 | 2/20 | 0.81 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.81 |
| ▸ | PKM | P14618 | 2/20 | 0.81 |
| ▸ | APEX1 | P27695 | 1/20 | 0.81 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.81 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.68 |
| ▸ | MAPT | P10636 | 3/20 | 0.68 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.65 |
| ▸ | CA12 | O43570 | 1/20 | 0.63 |
| ▸ | CA1 | P00915 | 1/20 | 0.63 |
| ▸ | CA2 | P00918 | 1/20 | 0.63 |
| ▸ | CA9 | Q16790 | 1/20 | 0.63 |
| ▸ | TP53 | P04637 | 2/20 | 0.62 |
| ▸ | NAMPT | P43490 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23898944 | 1.00 | RAB9A (0.81) | RAB9ANPC1POLBMEN1LMNA | |
| SCHEMBL678705 | 1.00 | RAB9A (0.81) | RAB9ANPC1POLBMEN1LMNA | |
| SCHEMBL16436156 | 1.00 | RAB9A (0.81) | RAB9ANPC1POLBMEN1LMNA | |
| SCHEMBL682875 | 1.00 | RAB9A (0.81) | RAB9ANPC1POLBMEN1LMNA | |
| SCHEMBL23805541 | 0.95 | NPC1 (0.73) | RAB9ANPC1POLBMEN1LMNA | |
| SCHEMBL1353478 | 0.90 | POLB (1.00) | RAB9ANPC1POLBMEN1LMNA | |
| SCHEMBL137276 | 0.90 | POLB (1.00) | RAB9ANPC1POLBMEN1LMNA | |
| SCHEMBL30319980 | 0.90 | POLB (1.00) | RAB9ANPC1POLBMEN1LMNA | |
| SCHEMBL2128727 | 0.90 | POLB (1.00) | RAB9ANPC1POLBMEN1LMNA | |
| SCHEMBL9681496 | 0.90 | POLB (1.00) | RAB9ANPC1POLBMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170327458-A1 | NOVEL CYSTOBACTAMIDES | Helmholtz-Zentrum für Infektionsforschung GmbH (DE) | 2017-11-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170327458-A1 | NOVEL CYSTOBACTAMIDES | SLC7A11, CTH, CBS | RAB9A 2066/4885NPC1 2674/4885POLB 3515/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.