SCHEMBL19601455

SCHEMBL19601455

CCC(=O)OCCOc1ccc(-c2nc(-c3ccccc3)nc(-c3ccccc3)n2)c(O)c1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.47
KMT2A Q03164 4/20 0.47
KDM4E B2RXH2 4/20 0.47
ALDH1A1 P00352 3/20 0.47
MEN1 O00255 3/20 0.47
SMN1; SMN2 Q16637 2/20 0.47
GBA1 P04062 1/20 0.47
LMNA P02545 3/20 0.43
HTT P42858 1/20 0.43
GAA P10253 1/20 0.43
MAPK10 P53779 1/20 0.43
CNR1 P21554 1/20 0.43
CNR2 P34972 1/20 0.43
GPR55 Q9Y2T6 1/20 0.43
HPGD P15428 2/20 0.42
PPARG P37231 3/20 0.41
MAPK1 P28482 4/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
PTPN11 Q06124 1/20 0.41
TP53 P04637 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12617445 0.91 DHODH (0.42) MAPTKMT2AKDM4EALDH1A1MEN1
SCHEMBL294861 0.89 PDE3B (0.46) MAPTKMT2AKDM4EMEN1SMN1; SMN2
SCHEMBL4825877 0.89 PDE3B (0.46) MAPTKMT2AKDM4EMEN1SMN1; SMN2
SCHEMBL12618037 0.88 PDK2 (0.41) MAPTKMT2AKDM4EMEN1SMN1; SMN2
SCHEMBL24915296 0.87 HDAC1 (0.42) CNR1CNR2GPR55PTPN11
SCHEMBL20433717 0.87 LMNA (0.40) MAPTKMT2AKDM4EMEN1SMN1; SMN2
SCHEMBL15599733 0.87 PDE3B (0.44) MAPTKMT2AKDM4EMEN1SMN1; SMN2
SCHEMBL12617451 0.87 CNR2 (0.49) CNR2PTPN11
SCHEMBL12617540 0.87 CNR2 (0.49) CNR2PTPN11
SCHEMBL31158097 0.87 CNR2 (0.49) CNR2PTPN11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9969702-B2 Triazine compound and synthetic resin composition using same ADEKA CORPORATION (JP) 2018-05-15 US disclosed
US-20170327475-A1 NOVEL TRIAZINE COMPOUND AND SYNTHETIC RESIN COMPOSITION USING SAME ADEKA CORPORATION (JP) 2017-11-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170327475-A1 NOVEL TRIAZINE COMPOUND AND SYNTHETIC RESIN COMPOSITION USING SAME PSMB5, SEM1, MRPS35 MAPT 1281/4885KMT2A 2277/4885KDM4E 2097/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.