SCHEMBL15599733

SCHEMBL15599733

CC(=O)OCCOc1ccc(-c2nc(-c3ccc(-c4ccccc4)cc3)nc(-c3ccc(-c4ccccc4)cc3)n2)c(O)c1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDE3B Q13370 2/20 0.44
PDE3A Q14432 2/20 0.44
P2RY12 Q9H244 2/20 0.44
KDM4E B2RXH2 3/20 0.43
RECQL P46063 1/20 0.43
MAPT P10636 4/20 0.41
LMNA P02545 4/20 0.41
NPSR1 Q6W5P4 3/20 0.41
MEN1 O00255 3/20 0.41
KMT2A Q03164 3/20 0.41
ALOX12 P18054 1/20 0.41
ALOX15 P16050 3/20 0.40
MAPK1 P28482 3/20 0.40
USP2 O75604 1/20 0.40
TP53 P04637 1/20 0.40
POLB P06746 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
HSD17B10 Q99714 1/20 0.40
GAA P10253 2/20 0.40
MAPK10 P53779 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL294861 0.98 PDE3B (0.46) PDE3BPDE3AP2RY12KDM4ERECQL
SCHEMBL4825877 0.98 PDE3B (0.46) PDE3BPDE3AP2RY12KDM4ERECQL
SCHEMBL12652439 0.89 PDE3B (0.45) PDE3BPDE3AP2RY12MAPTLMNA
SCHEMBL14274498 0.89 POLB (0.45) KDM4EMAPTLMNANPSR1MEN1
SCHEMBL580703 0.88 SIRT2 (0.48) PDE3BPDE3AP2RY12KDM4EMAPT
SCHEMBL29357152 0.88 SIRT2 (0.48) PDE3BPDE3AP2RY12KDM4EMAPT
SCHEMBL19601455 0.87 MAPT (0.47) KDM4EMAPTLMNANPSR1MEN1
SCHEMBL10090878 0.86 ADORA3 (0.46) KDM4ERECQLMAPTLMNANPSR1
SCHEMBL8518667 0.86 POLB (0.46) KDM4EMAPTLMNANPSR1MEN1
SCHEMBL2237946 0.86 POLB (0.46) KDM4EMAPTLMNANPSR1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2014026925-A1 STABLE UV ABSORBER COMPOSITION BASF SE (DE) 2014-02-20 WO disclosed