SCHEMBL294861

SCHEMBL294861

CC(=O)OCCOc1ccc(-c2nc(-c3ccccc3)nc(-c3ccccc3)n2)c(O)c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDE3B Q13370 3/20 0.46
PDE3A Q14432 3/20 0.46
P2RY12 Q9H244 3/20 0.46
KDM4E B2RXH2 3/20 0.45
RECQL P46063 1/20 0.45
MAPT P10636 3/20 0.42
NPSR1 Q6W5P4 3/20 0.42
LMNA P02545 3/20 0.42
MEN1 O00255 3/20 0.42
KMT2A Q03164 3/20 0.42
ALOX12 P18054 1/20 0.42
MAPK1 P28482 4/20 0.42
ALOX15 P16050 3/20 0.42
USP2 O75604 1/20 0.42
TP53 P04637 1/20 0.42
POLB P06746 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
HSD17B10 Q99714 1/20 0.42
GAA P10253 2/20 0.41
MAPK10 P53779 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4825877 1.00 PDE3B (0.46) PDE3BPDE3AP2RY12KDM4ERECQL
SCHEMBL15599733 0.98 PDE3B (0.44) PDE3BPDE3AP2RY12KDM4ERECQL
SCHEMBL19601455 0.89 MAPT (0.47) KDM4EMAPTNPSR1LMNAMEN1
SCHEMBL12652439 0.89 PDE3B (0.45) PDE3BPDE3AP2RY12MAPTNPSR1
SCHEMBL2237946 0.89 POLB (0.46) KDM4EMAPTNPSR1LMNAMEN1
SCHEMBL29512556 0.89 POLB (0.46) KDM4EMAPTNPSR1LMNAMEN1
SCHEMBL8518667 0.89 POLB (0.46) KDM4EMAPTNPSR1LMNAMEN1
SCHEMBL580703 0.88 SIRT2 (0.48) PDE3BPDE3AP2RY12KDM4EMAPT
SCHEMBL20433717 0.88 LMNA (0.40) KDM4EMAPTNPSR1LMNAMEN1
SCHEMBL29357152 0.88 SIRT2 (0.48) PDE3BPDE3AP2RY12KDM4EMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3578161-B1 METHOD FOR IMPROVING STORAGE STABILITY OF COSMETIC ADEKA CORP (JP) 2025-11-12 EP disclosed
EP-3763353-B1 METHOD FOR IMPROVING WATER SOLUBILITY OF SPARINGLY-SOLUBLE COMPONENT ADEKA CORP (JP) 2024-01-24 EP disclosed
US-11780990-B2 Particulate ultraviolet absorber and resin composition ADEKA CORPORATION (JP) 2023-10-10 US disclosed
US-11780990-B2 Particulate ultraviolet absorber and resin composition ADEKA CORPORATION (JP) 2023-10-10 US disclosed
EP-3603609-B1 COSMETIC EMULSION COMPOSITION ADEKA CORP (JP) 2022-04-13 EP disclosed
US-20210017360-A1 PARTICULATE ULTRAVIOLET ABSORBER AND RESIN COMPOSITION ADEKA CORPORATION (JP) 2021-01-21 US disclosed
EP-3763353-A1 METHOD FOR IMPROVING WATER SOLUBILITY OF SPARINGLY-SOLUBLE COMPONENT ADEKA CORPORATION (JP) 2021-01-13 EP disclosed
US-20200397675-A1 METHOD FOR IMPROVING SOLUBILITY OF SPARINGLY WATER-SOLUBLE COMPONENT ADEKA CORPORATION (JP) 2020-12-24 US disclosed
CN-111918635-A Method for improving solubility of poorly water-soluble components 株式会社ADEKA 2020-11-10 CN disclosed
EP-3603609-A1 COSMETIC EMULSION COMPOSITION ADEKA CORPORATION (JP) 2020-02-05 EP disclosed
US-20110272648-A1 ULTRAVIOLET ABSORBER COMPOSITION WITH IMPROVED HEAT RESISTANCE AND SYNTHETIC RESIN COMPOSITION CONTAINING THE SAME ADEKA CORPORATION (JP) 2011-11-10 US disclosed
US-20110272648-A1 ULTRAVIOLET ABSORBER COMPOSITION WITH IMPROVED HEAT RESISTANCE AND SYNTHETIC RESIN COMPOSITION CONTAINING THE SAME ADEKA CORPORATION (JP) 2011-11-10 US disclosed
US-20110121245-A1 OPTICAL FILM ADEKA CORPORATION (JP) 2011-05-26 US disclosed
US-7834084-B2 Light stabilizer emulsion composition and aqueous coating agent composition containing the same ADEKA CORPORATION (JP) 2010-11-16 US disclosed
US-7671096-B2 Light stabilizer emulsion composition ADEKA CORPORATION (JP) 2010-03-02 US disclosed
EP-1690897-B1 Light stabiliser emulsion composition ADEKA CORP (JP) 2008-04-09 EP disclosed
US-20070240615-A1 Light Stabilizer Emulsion Compositon and Aqueous Coating Agent Compositon Containing the Same ADEKA CORPORATION (JP) 2007-10-18 US disclosed
EP-1818382-A1 LIGHT STABILIZER EMULSION COMPOSITION AND AQUEOUS COATING COMPOSITION CONTAINING SAME Adeka Corporation (JP) 2007-08-15 EP disclosed
US-20060183824-A1 Light stabilizer emulsion composition ADEKA CORPORATION (JP) 2006-08-17 US disclosed
EP-1690897-A1 Light stabiliser emulsion composition Adeka Corporation (JP) 2006-08-16 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200397675-A1 METHOD FOR IMPROVING SOLUBILITY OF SPARINGLY WATER-SOLUBLE COMPONENT AQP1, GUCY1A2, NOS2 PDE3B 2179/4885PDE3A 2260/4885P2RY12 4728/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.