Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12463759 | 0.65 | KDM4E (0.35) | ALDH1A1KDM4EHTT | |
| SCHEMBL19605838 | 0.62 | JAK2 (0.32) | — | |
| SCHEMBL31701317 | 0.60 | ATR (0.42) | — | |
| SCHEMBL607884 | 0.60 | APLNR (0.40) | ALDH1A1MAPTKDM4EHTTCYP1A2 | |
| SCHEMBL17624116 | 0.58 | CHRM3 (0.35) | ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL14001335 | 0.58 | ALDH1A1 (0.33) | ALDH1A1MAPTGAATDP1HPGD | |
| SCHEMBL6431756 | 0.58 | BRD4 (0.30) | — | |
| SCHEMBL6431761 | 0.58 | BRD4 (0.30) | — | |
| SCHEMBL22131881 | 0.57 | ACACB (0.46) | TDP1 | |
| Thiopalmyrone SCHEMBL21648178 | 0.57 | CYP3A4 (0.33) | ALDH1A1MAPTCYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017197036-A1 | SPIROCYCLIC DEGRONIMERS FOR TARGET PROTEIN DEGRADATION | C4 THERAPEUTICS, INC. (US) | 2017-11-16 | — | — | WO | disclosed |