Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APLNR | P35414 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | AURKA | O14965 | 1/20 | 0.39 |
| ▸ | TTK | P33981 | 1/20 | 0.39 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.39 |
| ▸ | INCENP | Q9NQS7 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | CCR1 | P32246 | 1/20 | 0.36 |
| ▸ | CCR5 | P51681 | 1/20 | 0.36 |
| ▸ | CCR8 | P51685 | 1/20 | 0.36 |
| ▸ | BTK | Q06187 | 1/20 | 0.35 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.34 |
| ▸ | CCR4 | P51679 | 2/20 | 0.33 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.33 |
| ▸ | NOS3 | P29474 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22613006 | 0.84 | APLNR (0.36) | APLNRCYP1A2CYP2C19ALDH1A1AURKA | |
| SCHEMBL16579445 | 0.84 | HPGD (0.45) | APLNRALDH1A1MEN1KMT2AHTT | |
| SCHEMBL32689440 | 0.82 | — | — | |
| SCHEMBL422296 | 0.82 | — | — | |
| SCHEMBL10202612 | 0.82 | GAA (0.38) | APLNRCYP1A2CYP2C19ALDH1A1AURKA | |
| SCHEMBL28377948 | 0.82 | LRRK2 (0.41) | APLNRCYP1A2CYP2C19ALDH1A1AURKA | |
| SCHEMBL29606513 | 0.82 | ALDH1A1 (0.40) | APLNRALDH1A1AURKATTKAURKB | |
| SCHEMBL15633445 | 0.82 | ALDH1A1 (0.40) | APLNRALDH1A1AURKATTKAURKB | |
| SCHEMBL25401783 | 0.80 | — | — | |
| SCHEMBL30802832 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 61 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114276334-A | Carbazole alkylated aromatic heterocyclic derivative and preparation method thereof | 内蒙古民族大学 | 2022-04-05 | — | — | CN | claimed |
| CN-103333126-B | Method for nitratlon reaction on 2,6-dimethoxy pyrazine | INST CHEMICAL MATERIAL CHINA ACADEMY ENGINEERING PHYSICS | 2015-06-17 | — | — | CN | claimed |
| CN-103333126-A | Method for nitratlon reaction on 2,6-dimethoxy pyrazine | INST CHEMICAL MATERIAL CHINA ACADEMY ENGINEERING PHYSICS | 2013-10-02 | — | — | CN | claimed |
| US-20100035997-A1 | KIT FOR APPLYING A POLYMERIZABLE ADHESIVE COMPOSITION TO TISSUES | BROADLEY KENNETH N | 2010-02-11 | — | — | US | claimed |
| EP-2142223-A2 | KIT FOR APPLYING A POLYMERISABLE ADHESIVE COMPOSITION TO TISSUES | Henkel AG & Co. KGaA (DE) | 2010-01-13 | — | — | EP | claimed |
| WO-2008128903-A2 | KIT FOR APPLYING A POLYMERISABLE ADHESIVE COMPOSITION TO TISSUES | HENKEL AG & CO. KGAA (DE) | 2008-10-30 | — | — | WO | claimed |
| EP-1501825-A2 | SUBSTITUTED IMIDAZOLYLMETHYL PYRIDINE AND PYRAZINE DERIVATIVES: GABA A RECEPTOR LIGANDS | NEUROGEN CORPORATION (US) | 2005-02-02 | — | — | EP | claimed |
| WO-2004041809-A2 | SUBSTITUTED IMIDAZOLYLMETHYL PYRIDINE AND PYRAZINE DERIVATIVES AND THEIR USE AS GABAA RECEPTOR LIGANDS | NEUROGEN CORPORATION (US) | 2004-05-21 | — | — | WO | claimed |
| CN-114276334-B | Carbazole alkylation aromatic heterocyclic derivative and preparation method thereof | 内蒙古民族大学 | 2024-04-09 | — | — | CN | disclosed |
| CN-114276334-B | Carbazole alkylation aromatic heterocyclic derivative and preparation method thereof | 内蒙古民族大学 | 2024-04-09 | — | — | CN | disclosed |
| CN-114276334-A | Carbazole alkylated aromatic heterocyclic derivative and preparation method thereof | 内蒙古民族大学 | 2022-04-05 | — | — | CN | disclosed |
| CN-114276334-A | Carbazole alkylated aromatic heterocyclic derivative and preparation method thereof | 内蒙古民族大学 | 2022-04-05 | — | — | CN | disclosed |
| WO-2022015624-A1 | SUBSTITUTED DIHYDROPYRAZINEDIONES AS MODULATORS OF THE NMDA RECEPTOR | SCHRÖDINGER, INC. (US) | 2022-01-20 | — | — | WO | disclosed |
| WO-2022015624-A1 | SUBSTITUTED DIHYDROPYRAZINEDIONES AS MODULATORS OF THE NMDA RECEPTOR | SCHRÖDINGER, INC. (US) | 2022-01-20 | — | — | WO | disclosed |
| CN-1024797-C | Indole derivatives | OTSUKA CHEMICAL CO LTD (JP) | 1994-06-01 | — | — | CN | disclosed |
| US-5011847-A | 2,5-diaryl tetrahydrofurans and analogs thereof as PAF antagonists | MERCK & CO., INC. (US) | 1991-04-30 | — | — | US | disclosed |
| US-5001123-A | 2,5-diaryl tetrahydrofurans and analogs thereof as PAF antagonists | MERCK & CO., INC. (US) | 1991-03-19 | — | — | US | disclosed |
| CN-1049155-A | INDOLE DERIVATIVES | OTSUKA CHEMICAL CO LTD (JP) | 1991-02-13 | — | — | CN | disclosed |
| EP-0402156-A1 | New 2,5-diaryl tetrahydrofurans and analogs thereof as PAF antagonists | MERCK & CO. INC. (US) | 1990-12-12 | — | — | EP | disclosed |
| EP-0402155-A1 | New 2,5-diaryl tetrahydrofurans and analogs therof as PAF antagonists | MERCK & CO. INC. (US) | 1990-12-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100035997-A1 | KIT FOR APPLYING A POLYMERIZABLE ADHESIVE COMPOSITION TO TISSUES | KIT, TEKT1, CUTA | APLNR 765/4885CYP1A2 4512/4885CYP2C19 3961/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.