SCHEMBL6076792

SCHEMBL6076792

O=c1nc(I)c2ccccc2[nH]1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 6/20 0.58
ALDH1A1 P00352 5/20 0.58
HSD17B10 Q99714 4/20 0.58
HPGD P15428 2/20 0.58
TSHR P16473 1/20 0.58
APP P05067 2/20 0.49
LMNA P02545 2/20 0.48
GLA P06280 1/20 0.48
GAA P10253 1/20 0.48
HTT P42858 1/20 0.48
ATM Q13315 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
ADORA3 P0DMS8 3/20 0.47
PARP1 P09874 4/20 0.45
GPR3 P46089 2/20 0.45
MEN1 O00255 2/20 0.45
KMT2A Q03164 2/20 0.45
CYP1A2 P05177 2/20 0.45
TNKS2 Q9H2K2 2/20 0.45
TNKS O95271 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29844822 0.76 KDM4E (0.58) KDM4EALDH1A1HSD17B10HPGDTSHR
SCHEMBL30293081 0.76 ALDH1A1 (0.58) KDM4EALDH1A1HSD17B10HPGDTSHR
SCHEMBL6099088 0.76 KDM4E (0.58) KDM4EALDH1A1HSD17B10HPGDTSHR
SCHEMBL3139711 0.76 KDM4E (0.58) KDM4EALDH1A1HSD17B10HPGDTSHR
SCHEMBL554709 0.76 KDM4E (0.58) KDM4EALDH1A1HSD17B10HPGDTSHR
SCHEMBL530191 0.76 ALDH1A1 (0.58) KDM4EALDH1A1HSD17B10HPGDTSHR
Benzoylenurea SCHEMBL29947820 0.76 ALDH1A1 (0.58) KDM4EALDH1A1HSD17B10HPGDTSHR
SCHEMBL4413903 0.76 KDM4E (0.58) KDM4EALDH1A1HSD17B10HPGDTSHR
SCHEMBL196018 0.76 KDM4E (0.58) KDM4EALDH1A1HSD17B10HPGDTSHR
SCHEMBL1867417 0.76 ALDH1A1 (0.58) KDM4EALDH1A1HSD17B10HPGDTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 213 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115666240-A Fungicidal compositions 先正达农作物保护股份公司 2023-01-31 CN claimed
CN-110740644-B Fungicidal compositions 先正达参股股份有限公司 2021-09-28 CN claimed
CN-110740644-A Fungicidal compositions 先正达参股股份有限公司 2020-01-31 CN claimed
CN-121586714-A Connected bicyclic compounds for control and combating invertebrate pests FMC公司 2026-02-27 CN disclosed
CN-115702153-B Microbiocidal derivatives 先正达农作物保护股份公司 2025-06-24 CN disclosed
CN-120004791-A Quaternary ring amide compound and application thereof 青岛清原化合物有限公司 2025-05-16 CN disclosed
CN-119998269-A Microbiocidal pyrazole derivatives 先正达农作物保护股份公司 2025-05-13 CN disclosed
CN-119998270-A Microbiocidal pyrazole derivatives 先正达农作物保护股份公司 2025-05-13 CN disclosed
CN-119907790-A Pyrazole amide insecticidal agents FMC公司 2025-04-29 CN disclosed
CN-119855495-A New application of fluxapyroxad hydroxylamine 先正达农作物保护股份公司 2025-04-18 CN disclosed
CN-119677724-A Crystalline forms of 1,2, 4-oxadiazole fungicides 先正达农作物保护股份公司 2025-03-21 CN disclosed
CN-110799035-A Fungicidal compositions 先正达参股股份有限公司 2020-02-14 CN disclosed
CN-110770223-A Pesticidally active pyrazole derivatives 先正达参股股份有限公司 2020-02-07 CN disclosed
CN-110740644-A Fungicidal compositions 先正达参股股份有限公司 2020-01-31 CN disclosed
CN-110709395-A Microbicidal oxadiazole derivatives 先正达参股股份有限公司 2020-01-17 CN disclosed
US-7081460-B2 Quinazoline and quinazoline-like compounds for the treatment of integrin-mediated disorders ORTHO-MCNEIL PHARMACEUTICAL, INC. (US) 2006-07-25 US disclosed
EP-1389205-B1 QUINAZOLINE AND QUINAZOLINE-LIKE COMPOUNDS FOR THE TREATMENT OF INTEGRIN-MEDIATED DISORDERS ORTHO MCNEIL PHARMACEUTICAL RE (US) 2005-12-21 EP disclosed
EP-1389205-A1 QUINAZOLINE AND QUINAZOLINE-LIKE COMPOUNDS FOR THE TREATMENT OF INTEGRIN-MEDIATED DISORDERS Ortho-McNeil Pharmaceutical Research Inc. (US) 2004-02-18 EP disclosed
US-20030139398-A1 Quinazoline and quinazoline-like compounds for the treatment of integrin-mediated disorders ORTHO-MCNEIL PHARMACEUTICAL, INC. 2003-07-24 US disclosed
WO-2002081467-A1 QUINAZOLINE AND QUINAZOLINE-LIKE COMPOUNDS FOR THE TREATMENT OF INTEGRIN-MEDIATED DISORDERS ORTHO-MCNEIL PHARMACEUTICAL, INC. (US) 2002-10-17 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030139398-A1 Quinazoline and quinazoline-like compounds for the treatment of integrin-mediated disorders ITGB2, ITGB5, ITGB3 KDM4E 3753/4885ALDH1A1 2165/4885HSD17B10 4658/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.