Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.58 |
| ▸ | HPGD | P15428 | 2/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | TNKS2 | Q9H2K2 | 2/20 | 0.50 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | DAO | P14920 | 1/20 | 0.50 |
| ▸ | DDO | Q99489 | 1/20 | 0.50 |
| ▸ | TNKS | O95271 | 1/20 | 0.50 |
| ▸ | PARP1 | P09874 | 1/20 | 0.50 |
| ▸ | GPR3 | P46089 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.50 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30293081 | 1.00 | ALDH1A1 (0.58) | ALDH1A1KDM4EHSD17B10HPGDTSHR | |
| Acetic Acid SCHEMBL6510410 | 0.90 | KDM4E (0.53) | ALDH1A1KDM4EHSD17B10HPGDTSHR | |
| SCHEMBL30095710 | 0.87 | ALDH1A1 (0.53) | ALDH1A1KDM4EHSD17B10HPGDTSHR | |
| SCHEMBL27527528 | 0.78 | ALDH1A1 (0.48) | ALDH1A1KDM4EHSD17B10HPGDTSHR | |
| SCHEMBL6818663 | 0.77 | PARP1 (0.52) | ALDH1A1KDM4EHSD17B10HPGDCYP1A2 | |
| SCHEMBL6908303 | 0.77 | ALDH1A1 (0.53) | ALDH1A1KDM4EHSD17B10HPGDTSHR | |
| SCHEMBL6764919 | 0.77 | TYMS (0.50) | ALDH1A1KDM4EHSD17B10HPGDTSHR | |
| SCHEMBL3139711 | 0.76 | KDM4E (0.58) | ALDH1A1KDM4EHSD17B10HPGDTSHR | |
| SCHEMBL196018 | 0.76 | KDM4E (0.58) | ALDH1A1KDM4EHSD17B10HPGDTSHR | |
| SCHEMBL6099088 | 0.76 | KDM4E (0.58) | ALDH1A1KDM4EHSD17B10HPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 69 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111849001-A | Preparation method of waterproof total heat exchange paper | 绍兴百立盛新材料科技有限公司 | 2020-10-30 | — | — | CN | claimed |
| EP-2298769-B1 | Xanthin derivatives, their production and utilisation as medicine | BOEHRINGER INGELHEIM PHARMA (DE) | 2013-10-30 | — | — | EP | claimed |
| US-20130165428-A1 | XANTHINE DERIVATIVES, THE PREPARATION THEREOF AND THEIR USE AS PHARMACEUTICAL COMPOSITIONS | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2013-06-27 | — | — | US | claimed |
| US-20120252782-A1 | Xanthine Derivatives, the Preparation Thereof and Their Use as Pharmaceutical Compositions | BOEHRINGER INGELHEIM PHARMA GMBH AND CO. KG (DE) | 2012-10-04 | — | — | US | claimed |
| US-20120035158-A1 | Xanthine Derivatives, the Preparation Thereof and Their Use as Pharmaceutical Compositions | BOEHRINGER INGELHEIM PHARMA GMBH AND CO. KG (DE) | 2012-02-09 | — | — | US | claimed |
| US-20110144083-A1 | Xanthine Derivatives, the Preparation Thereof and Their Use as Pharmaceutical Compositions | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2011-06-16 | — | — | US | claimed |
| US-20100173916-A1 | Xanthine Derivatives, the Preparation Thereof and Their Use as Pharmaceutical Compositions | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-07-08 | — | — | US | claimed |
| EP-1757606-B1 | Xanthinderivatives for use as medical agents and the preparation thereof | BOEHRINGER INGELHEIM PHARMA (DE) | 2009-05-06 | — | — | EP | claimed |
| EP-1368349-B1 | XANTHINE DERIVATIVE, PRODUCTION AND USE THEREOF AS A MEDICAMENT | BOEHRINGER INGELHEIM PHARMA (DE) | 2007-02-14 | — | — | EP | claimed |
| US-20060205711-A1 | Xanthine derivatives, the preparation thereof and their use as pharmaceutical compositions | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2006-09-14 | — | — | US | claimed |
| WO-2005037839-A1 | NORCANTHARIDIN DERIVATIVE COMPOUNDS, METHOD FOR THE PRODUCTION THEREOF, COMPOSITIONS CONTAINING SAID COMPOUNDS AND THE USE THEREOF | ENTOMED (FR) | 2005-04-28 | — | — | WO | claimed |
| US-20040077645-A1 | Dipeptidyl aminopeptidase inhibitors; diabetes mellitus, arthritis, obesity, allograft transplantation and osteoporosis treatment | BOEHRINGER INGELHEIM PHARMA GMBH & CO KG (DE) | 2004-04-22 | — | — | US | claimed |
| EP-3840748-B1 | SUBSTITUTED IMIDAZOLES FOR THE INHIBITION OF TGF-BETA AND METHODS OF TREATMENT | CLAVIUS PHARMACEUTICALS LLC (US) | 2026-04-15 | — | — | EP | disclosed |
| CN-118791472-A | Novel methyl quinazolinone derivatives | 豪夫迈·罗氏有限公司 | 2024-10-18 | — | — | CN | disclosed |
| CN-118791472-A | Novel methyl quinazolinone derivatives | 豪夫迈·罗氏有限公司 | 2024-10-18 | — | — | CN | disclosed |
| US-12077548-B2 | Substituted imidazoles for the inhibition of TGF-β and methods of treatment | Clavius Pharmaceuticals, LLC. (US) | 2024-09-03 | — | — | US | disclosed |
| US-4546075-A | TETRAZOLE, BENZOTHIAZOLE, BENZOXAZOLE, OR BENZIMIDAZOLE COMPOUNDS | FUJI PHOTO FILM CO., LTD. (JP) | 1985-10-08 | — | — | US | disclosed |
| US-4452885-A | USING THRIHALOMETHYL-3,4-OXADIAZOLES AS ANTIFOGGING AGENTS | FUJI PHOTO FILM CO., LTD. (JP) | 1984-06-05 | — | — | US | disclosed |
| EP-0107398-A1 | Ortho substituted dihydroxy-2(1H)quinazolinone-1-alkanoic acids | ORTHO PHARMACEUTICAL CORPORATION (US) | 1984-05-02 | — | — | EP | disclosed |
| US-4291120-A | VINYLPHENOL POLYMER AS ADHESION IMPROVER | FUJI PHOTO FILM CO., LTD. (JP) | 1981-09-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12077548-B2 | Substituted imidazoles for the inhibition of TGF-β and methods of treatment | TGFB1, TGFBR1, TGFB2 | ALDH1A1 2900/4885KDM4E 1077/4885HSD17B10 2759/4885 |
| US-20110144083-A1 | Xanthine Derivatives, the Preparation Thereof and Their Use as Pharmaceutical Compositions | DPP4, DPP3, DPP7 | ALDH1A1 238/4885KDM4E 1166/4885HSD17B10 1124/4885 |
| US-20130165428-A1 | XANTHINE DERIVATIVES, THE PREPARATION THEREOF AND THEIR USE AS PHARMACEUTICAL COMPOSITIONS | DPP4, DPP3, DPP7 | ALDH1A1 238/4885KDM4E 1166/4885HSD17B10 1124/4885 |
| US-20100173916-A1 | Xanthine Derivatives, the Preparation Thereof and Their Use as Pharmaceutical Compositions | DPP4, DPP3, DPP7 | ALDH1A1 238/4885KDM4E 1166/4885HSD17B10 1124/4885 |
| US-20060205711-A1 | Xanthine derivatives, the preparation thereof and their use as pharmaceutical compositions | DPP4, DPP3, DPP7 | ALDH1A1 238/4885KDM4E 1166/4885HSD17B10 1124/4885 |
| US-20120035158-A1 | Xanthine Derivatives, the Preparation Thereof and Their Use as Pharmaceutical Compositions | DPP4, DPP3, DPP7 | ALDH1A1 238/4885KDM4E 1166/4885HSD17B10 1124/4885 |
| US-20120252782-A1 | Xanthine Derivatives, the Preparation Thereof and Their Use as Pharmaceutical Compositions | DPP4, DPP3, DPP7 | ALDH1A1 238/4885KDM4E 1166/4885HSD17B10 1124/4885 |
| US-20040077645-A1 | Dipeptidyl aminopeptidase inhibitors; diabetes mellitus, arthritis, obesity, allograft transplantation and osteoporosis treatment | DPP4, DPP3, DPP7 | ALDH1A1 178/4885KDM4E 933/4885HSD17B10 897/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.