Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 6/20 | 0.47 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.40 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20778366 | 0.78 | ABHD6 (0.48) | MGLLPLA2G7ABHD6 | |
| SCHEMBL19603375 | 0.75 | TACR1 (0.34) | — | |
| SCHEMBL20570228 | 0.74 | TACR1 (0.45) | — | |
| SCHEMBL30458103 | 0.74 | TACR1 (0.45) | — | |
| SCHEMBL19603186 | 0.72 | MGLL (0.38) | MGLL | |
| SCHEMBL19603288 | 0.69 | MGLL (0.69) | MGLL | |
| SCHEMBL19603354 | 0.68 | MGLL (0.61) | MGLLPLA2G7ABHD6 | |
| SCHEMBL19603184 | 0.68 | MGLL (0.57) | MGLLPLA2G7ABHD6 | |
| SCHEMBL20769548 | 0.68 | MGLL (0.51) | MGLLABHD6 | |
| SCHEMBL19603236 | 0.67 | MGLL (0.57) | MGLLPLA2G7ABHD6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017197192-A1 | SPIROCYCLE COMPOUNDS AND METHODS OF MAKING AND USING SAME | ABIDE THERAPEUTICS, INC. (US) | 2017-11-16 | — | — | WO | disclosed |