Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | NAMPT | P43490 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20570228 | 1.00 | TACR1 (0.45) | TACR1EPHX2GPR119HDAC1HDAC2 | |
| SCHEMBL30458402 | 0.81 | TACR1 (0.42) | TACR1EPHX2GPR119HDAC1HDAC8 | |
| SCHEMBL20569877 | 0.81 | TACR1 (0.42) | TACR1EPHX2GPR119HDAC1HDAC8 | |
| SCHEMBL14279760 | 0.81 | ANO1 (0.47) | TACR1GPR119HDAC1HDAC2SMN1; SMN2 | |
| SCHEMBL20766101 | 0.81 | HDAC2 (0.51) | TACR1HDAC1HDAC2SMN1; SMN2MEN1 | |
| SCHEMBL3658891 | 0.80 | SMN1; SMN2 (0.46) | TACR1HDAC1HDAC2SMN1; SMN2MEN1 | |
| SCHEMBL20566981 | 0.80 | TACR1 (0.47) | TACR1EPHX2GPR119HDAC1HDAC2 | |
| SCHEMBL18064777 | 0.79 | IDO1 (0.46) | CYP2C19CYP2C9 | |
| SCHEMBL3661148 | 0.79 | GPR119 (0.44) | TACR1GPR119NAMPT | |
| SCHEMBL2798269 | 0.78 | KEAP1 (0.44) | GPR119MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110678177-B | Pyrazole MAGL inhibitors | H.隆德贝克有限公司 | 2023-06-13 | — | — | CN | disclosed |