Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.60 |
| ▸ | PPARA | Q07869 | 8/20 | 0.56 |
| ▸ | PPARG | P37231 | 7/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ELANE | P08246 | 2/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 2/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5141872 | 1.00 | ADORA3 (0.60) | ADORA3PPARAPPARGMEN1KMT2A | |
| SCHEMBL5369095 | 1.00 | ADORA3 (0.60) | ADORA3PPARAPPARGMEN1KMT2A | |
| SCHEMBL11548490 | 0.87 | ADORA3 (0.61) | ADORA3PPARAPPARGMEN1KMT2A | |
| SCHEMBL5531801 | 0.86 | ADORA3 (0.47) | ADORA3PPARAPPARGMEN1KMT2A | |
| SCHEMBL13846158 | 0.86 | ADORA3 (0.60) | ADORA3PPARAPPARGOPRK1ALDH1A1 | |
| SCHEMBL8935672 | 0.86 | ADORA3 (0.60) | ADORA3PPARAPPARGMEN1KMT2A | |
| SCHEMBL8935669 | 0.86 | ADORA3 (0.60) | ADORA3PPARAPPARGMEN1KMT2A | |
| SCHEMBL1960387 | 0.85 | PPARG (0.62) | ADORA3PPARAPPARGMEN1KMT2A | |
| SCHEMBL28567745 | 0.85 | ESR1 (0.49) | ADORA3PPARAPPARGMEN1KMT2A | |
| SCHEMBL10151372 | 0.84 | ADORA3 (0.58) | ADORA3PPARAPPARGOPRK1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7230129-B2 | Process for the preparation of optically pure isomers of 2-(4-hydroxy phenoxy)-2-methyl-butyric acid methyl ester | DR. REDDY'S LABORATORIES LIMITED (IN) | 2007-06-12 | — | — | US | claimed |
| US-20060194980-A1 | Process for the preparation of optically pure isomers of 2-(4-hydroxy phenoxy)-2-methyl-butyric acid methyl ester | DR. REDDY'S LABORATORIES LIMITED (IN) | 2006-08-31 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060194980-A1 | Process for the preparation of optically pure isomers of 2-(4-hydroxy phenoxy)-2-methyl-butyric acid methyl ester | HBB, GABBR2, GABRB2 | ADORA3 2803/4885PPARA 2134/4885PPARG 2787/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.