Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADK | P55263 | 8/20 | 0.36 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.34 |
| ▸ | TOP2A | P11388 | 4/20 | 0.33 |
| ▸ | PRMT5 | O14744 | 3/20 | 0.33 |
| ▸ | METTL3 | Q86U44 | 2/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10178599 | 1.00 | ADK (0.36) | ADKSLC29A1TOP2APRMT5METTL3 | |
| SCHEMBL10178238 | 0.92 | ADK (0.35) | ADKSLC29A1TOP2APRMT5METTL3 | |
| SCHEMBL19033109 | 0.92 | ADK (0.40) | ADKSLC29A1PRMT5METTL3HIF1A | |
| SCHEMBL16728050 | 0.91 | ADK (0.35) | ADKSLC29A1PRMT5METTL3HIF1A | |
| SCHEMBL14680069 | 0.91 | ADK (0.35) | ADKSLC29A1PRMT5METTL3HIF1A | |
| SCHEMBL10178145 | 0.87 | ADK (0.47) | ADKSLC29A1TOP2APRMT5METTL3 | |
| SCHEMBL19603993 | 0.87 | ADK (0.47) | ADKSLC29A1TOP2APRMT5METTL3 | |
| SCHEMBL19033104 | 0.85 | ADK (0.39) | ADKSLC29A1PRMT5METTL3HIF1A | |
| SCHEMBL19603994 | 0.84 | ADK (0.36) | ADKSLC29A1TOP2APRMT5METTL3 | |
| SCHEMBL10178142 | 0.84 | ADK (0.36) | ADKSLC29A1TOP2APRMT5METTL3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3670523-B1 | 3'-OH UNBLOCKED, FAST PHOTOCLEAVABLE TERMINATING NUCLEOTIDES AND THEIR USE IN METHODS FOR NUCLEIC ACID SEQUENCING | AGILENT TECHNOLOGIES INC (US) | 2021-08-11 | — | — | EP | disclosed |
| US-11001886-B2 | 3′-OH unblocked, fast photocleavable terminating nucleotides and methods for nucleic acid sequencing | AGILENT TECHNOLOGIES, INC. (US) | 2021-05-11 | — | — | US | disclosed |
| EP-3670523-A1 | 5-METHOXY. 3'-OH UNBLOCKED, FAST PHOTOCLEAVABLE TERMINATING NUCLEOTIDES AND METHODS FOR NUCLEIC ACID SEQUENCING | Agilent Technologies, Inc. (US) | 2020-06-24 | — | — | EP | disclosed |
| EP-2755984-B1 | 5-METHOXY. 3'-OH UNBLOCKED, FAST PHOTOCLEAVABLE TERMINATING NUCLEOTIDES AND METHODS FOR NUCLEIC ACID SEQUENCING | AGILENT TECHNOLOGIES INC (US) | 2020-02-12 | — | — | EP | disclosed |
| US-20190127790-A1 | 3'-OH UNBLOCKED, FAST PHOTOCLEAVABLE TERMINATING NUCLEOTIDES AND METHODS FOR NUCLEIC ACID SEQUENCING | AGILENT TECHNOLOGIES, INC. | 2019-05-02 | — | — | US | disclosed |
| US-10041115-B2 | 3′-OH unblocked, fast photocleavable terminating nucleotides and methods for nucleic acid sequencing | LASERGEN, INC. (US) | 2018-08-07 | — | — | US | disclosed |
| EP-2307565-B1 | REVERSIBLE NUCLEOSIDES AND NUCLEOTIDES TERMINATORS AND THEIR USE IN DNA SEQUENCING | LASERGEN INC (US) | 2017-11-29 | — | — | EP | disclosed |
| US-20170327886-A1 | 3'-OH UNBLOCKED, FAST PHOTOCLEAVABLE TERMINATING NUCLEOTIDES AND METHODS FOR NUCLEIC ACID SEQUENCING | LASERGEN, INC. (US) | 2017-11-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190127790-A1 | 3'-OH UNBLOCKED, FAST PHOTOCLEAVABLE TERMINATING NUCLEOTIDES AND METHODS FOR NUCLEIC ACID SEQUENCING | RNGTT, NT5C3B, NSUN2 | ADK 688/4885SLC29A1 363/4885TOP2A 156/4885 |
| US-10041115-B2 | 3′-OH unblocked, fast photocleavable terminating nucleotides and methods for nucleic acid sequencing | RNGTT, NT5C3B, NSUN2 | ADK 656/4885SLC29A1 352/4885TOP2A 147/4885 |
| US-11001886-B2 | 3′-OH unblocked, fast photocleavable terminating nucleotides and methods for nucleic acid sequencing | RNGTT, NT5C3B, NSUN2 | ADK 656/4885SLC29A1 352/4885TOP2A 147/4885 |
| US-20170327886-A1 | 3'-OH UNBLOCKED, FAST PHOTOCLEAVABLE TERMINATING NUCLEOTIDES AND METHODS FOR NUCLEIC ACID SEQUENCING | RNGTT, NT5C3B, NSUN2 | ADK 688/4885SLC29A1 363/4885TOP2A 156/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.