Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.66 |
| ▸ | POLB | P06746 | 2/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | ATM | Q13315 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | FAAH | O00519 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.53 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.53 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19403152 | 1.00 | LMNA (0.66) | LMNAPOLBALDH1A1SMN1; SMN2ATM | |
| SCHEMBL15363580 | 1.00 | LMNA (0.66) | LMNAPOLBALDH1A1SMN1; SMN2ATM | |
| SCHEMBL26316648 | 0.94 | HRH3 (0.61) | LMNAPOLBALDH1A1SMN1; SMN2ATM | |
| SCHEMBL23977354 | 0.92 | LMNA (0.60) | LMNAPOLBALDH1A1SMN1; SMN2ATM | |
| SCHEMBL24115228 | 0.91 | LMNA (0.55) | LMNAPOLBALDH1A1SMN1; SMN2ATM | |
| SCHEMBL26908807 | 0.90 | LMNA (0.54) | LMNAPOLBALDH1A1SMN1; SMN2ATM | |
| SCHEMBL22361385 | 0.86 | KDM4E (0.63) | POLBALDH1A1SMN1; SMN2ATMKDM4E | |
| SCHEMBL18292063 | 0.86 | KDM4E (0.63) | POLBALDH1A1SMN1; SMN2ATMKDM4E | |
| SCHEMBL18292042 | 0.86 | KDM4E (0.63) | POLBALDH1A1SMN1; SMN2ATMKDM4E | |
| SCHEMBL15867646 | 0.85 | ALDH1A1 (0.59) | LMNAPOLBALDH1A1SMN1; SMN2ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024052333-A1 | MULTIVALENT FIBROBLAST ACTIVATION PROTEIN LIGANDS FOR TARGETED DELIVERY APPLICATIONS | PHILOCHEM AG (CH) | 2024-03-14 | — | — | WO | disclosed |
| WO-2023144379-A1 | HIGH-AFFINITY LIGANDS OF FIBROBLAST ACTIVATION PROTEIN FOR TARGETED DELIVERY APPLICATIONS | PHILOCHEM AG (CH) | 2023-08-03 | — | — | WO | disclosed |
| EP-3455222-B1 | NUCLEAR IMAGING AND RADIOTHERAPEUTICS AGENTS TARGETING CARBONIC ANHYDRASE IX AND USES THEREOF | UNIV JOHNS HOPKINS (US) | 2022-03-02 | — | — | EP | disclosed |
| WO-2017197251-A1 | NUCLEAR IMAGING AND RADIOTHERAPEUTICS AGENTS TARGETING CARBONIC ANHYDRASE IX AND USES THEREOF | THE JOHNS HOPKINS UNIVERSITY (US) | 2017-11-16 | — | — | WO | disclosed |